Browse our phosphofructokinase, Muscle Proteins (PFKM)

Three phosphofructokinase isozymes exist in humans muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.

• phosphofructokinase, muscle (PFKM)
• phosphofructokinase, muscle (Pfkm)
• phosphofructokinase, muscle a (pfkma)
• phosphofructokinase, muscle S homeolog (pfkm.S)

• AI131669 protein
• GSD7 protein
• M-PFK protein
• pfk protein
• PFK-1 protein
• Show all synonym aliases
• Pfk-4 protein
• PFK-A protein
• Pfk-M protein
• PFK1 protein
• Pfk4 protein
• Pfka protein
• pfkm protein
• Pfkx protein
• zgc:92344 protein

6-phosphofructo-1-kinase , 6-phosphofructokinase, muscle type , PFK-A , phosphofructo-1-kinase isozyme A , phosphofructokinase 1 , phosphofructokinase, polypeptide X , phosphofructokinase-M , phosphohexokinase , phosphofructokinase 4 , phosphofructokinase-1 A isozyme , phosphofructokinase-M (connecting peptide) , phosphofructokinase-A , 6-phosphofructokinase muscle type , muscle type phosphofructokinase , muscle phosphofructokinase , muscle-type phosphofructokinase , ATP-dependent 6-phosphofructokinase, muscle type , phosphofructokinase, muscle S homeolog