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PFKM Protein (His tag)

PFKM Origin: Human Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318896
  • Target See all PFKM Proteins
    PFKM (phosphofructokinase, Muscle (PFKM))
    Protein Type
    Recombinant
    Origin
    • 7
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human Cells
    Purification tag / Conjugate
    This PFKM protein is labelled with His tag.
    Purpose
    Recombinant Human PFK1/PFKM Protein (His Tag)
    Sequence
    Thr 2-Val 780
    Characteristics
    Recombinant Human PhosphoFructoKinase, Muscle type is produced by our Mammalian expression system and the target gene encoding Thr2-Val780 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product PFKM Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    PFKM (phosphofructokinase, Muscle (PFKM))
    Alternative Name
    PFK1/PFKM (PFKM Products)
    Synonyms
    GSD7 Protein, PFK-1 Protein, PFK1 Protein, PFKA Protein, PFKX Protein, AI131669 Protein, PFK-A Protein, PFK-M Protein, Pfk-4 Protein, Pfk4 Protein, Pfka Protein, Pfkx Protein, Pfk-M Protein, M-PFK Protein, PFKM Protein, pfkm Protein, zgc:92344 Protein, pfk Protein, im:7137110 Protein, wu:fc58g11 Protein, phosphofructokinase, muscle Protein, phosphofructokinase, platelet Protein, phosphofructokinase, muscle a Protein, phosphofructokinase, muscle S homeolog Protein, phosphofructokinase, muscle b Protein, PFKM Protein, Pfkm Protein, PFKP Protein, pfkma Protein, pfkm.S Protein, pfkmb Protein
    Background

    Background: 6-phosphofructokinase, muscle type is a muscle-type isozyme that in humans is encoded by the PFKM gene. It belongs to the phosphofructokinase family and Two domains subfamily. PFKM functions as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. PFK1 converts fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP.

    Synonym: 6-phosphofructokinase, muscle type,Phosphofructo-1-kinase isozyme A,Phosphofructokinase 1,Phosphohexokinase,PFKM,PFKX,ATP-PFK,GSD7,PFK-1,PFK1,PFKA,PPP1R122

    Molecular Weight
    86.1 kDa
    UniProt
    P08237
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
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