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Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Products

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))

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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008].

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Featured Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Categories

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Antibodies

High quality antibodies with extensive validation data.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B ELISA Kits

Reliable ELISA kits for a wide range of species.

Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IP, IF, PLA, RNAi
Validations
  • (7)
Cat. No. ABIN562341
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Rat
Application WB, FACS
Validations
  • (5)
Cat. No. ABIN1500376
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IF
Validations
  • (5)
Cat. No. ABIN1500371
Quantity 100 μL
Datasheet Datasheet

Recommended Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958949
Quantity 96 tests
Datasheet Datasheet

Recommended Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1315907
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133917
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086363
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B products

Yien, Bieker: "Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2Cβ." in: The Journal of biological chemistry, Vol. 287, Issue 19, pp. 15193-204, (2012) (PubMed).

Parvari, Gonen, Alshafee, Buriakovsky, Regev, Hershkovitz: "The 2p21 deletion syndrome: characterization of the transcription content." in: Genomics, Vol. 86, Issue 2, pp. 195-211, (2005) (PubMed).

Prajapati, Verma, Yamamoto, Kwak, Gaynor: "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, (2004) (PubMed).

Seroussi, Shani, Ben-Meir, Chajut, Divinski, Faier, Gery, Karby, Kariv-Inbal, Sella, Smorodinsky, Lavi: "Uniquely conserved non-translated regions are involved in generation of the two major transcripts of protein phosphatase 2Cbeta." in: Journal of molecular biology, Vol. 312, Issue 3, pp. 439-51, (2001) (PubMed).

Synonyms and alternative names related to Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B

protein phosphatase, Mg2+/Mn2+ dependent 1B (PPM1B), protein phosphatase 1B, magnesium dependent, beta isoform (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent, 1B (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent, 1Bb (ppm1bb), protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog (ppm1b.L), protein phosphatase, Mg2+/Mn2+ dependent 1B (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent, 1Ba (ppm1ba), fc18g04, PP2C-beta-X, pp2c-beta-x, Pp2c2, PP2CB, pp2cb, PP2CBETA, pp2cbeta, PPC2BETAX, ppc2betax, ppm1a, wu:fc18g04, zgc:92031, zgc:92329

Protein level used designations for Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B

  • PP2C-beta
  • protein phosphatase 1B
  • protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform
  • protein phosphatase 2C isoform beta
  • protein phosphatase 2C-like protein
  • Protein phosphatase type 1B (formely 2C) Mg-dependent beta isoform
  • Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform
  • protein phosphatase 1B, magnesium dependent, beta isoform
  • protein phosphatase 1A, magnesium dependent, alpha
  • protein phosphatase 1A, magnesium dependent, alpha isoform
  • protein phosphatase type 2C beta
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