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PPM1B Products

(Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))

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The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq, Jul 2008].

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Featured PPM1B Categories

PPM1B Antibodies

High quality antibodies with extensive validation data.

PPM1B ELISA Kits

Reliable ELISA kits for a wide range of species.

PPM1B Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPM1B Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IF, IP, PLA, RNAi, ELISA, WB
Validations
  • (7)
Cat. No. ABIN562341
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application FACS, IF, WB
Validations
  • (5)
Cat. No. ABIN1500371
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Rat
Application FACS, WB
Validations
  • (5)
Cat. No. ABIN1500376
Quantity 100 μL
Datasheet Datasheet

Recommended PPM1B ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6958949
Quantity 96 tests
Datasheet Datasheet

Recommended PPM1B Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3133917
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3086363
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN5710135
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our PPM1B products

Yien, Bieker: "Functional interactions between erythroid Krüppel-like factor (EKLF/KLF1) and protein phosphatase PPM1B/PP2Cβ." in: The Journal of biological chemistry, Vol. 287, Issue 19, pp. 15193-204, (2012) (PubMed).

Parvari, Gonen, Alshafee, Buriakovsky, Regev, Hershkovitz: "The 2p21 deletion syndrome: characterization of the transcription content." in: Genomics, Vol. 86, Issue 2, pp. 195-211, (2005) (PubMed).

Prajapati, Verma, Yamamoto, Kwak, Gaynor: "Protein phosphatase 2Cbeta association with the IkappaB kinase complex is involved in regulating NF-kappaB activity." in: The Journal of biological chemistry, Vol. 279, Issue 3, pp. 1739-46, (2004) (PubMed).

Seroussi, Shani, Ben-Meir, Chajut, Divinski, Faier, Gery, Karby, Kariv-Inbal, Sella, Smorodinsky, Lavi: "Uniquely conserved non-translated regions are involved in generation of the two major transcripts of protein phosphatase 2Cbeta." in: Journal of molecular biology, Vol. 312, Issue 3, pp. 439-51, (2001) (PubMed).

Synonyms and alternative names related to PPM1B

protein phosphatase, Mg2+/Mn2+ dependent 1B (PPM1B), protein phosphatase 1B, magnesium dependent, beta isoform (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent, 1B (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent 1B L homeolog (ppm1b.L), protein phosphatase, Mg2+/Mn2+ dependent 1B (Ppm1b), protein phosphatase, Mg2+/Mn2+ dependent, 1Ba (ppm1ba), PP2C-beta-X, pp2c-beta-x, Pp2c2, PP2CB, pp2cb, PP2CBETA, pp2cbeta, PPC2BETAX, ppc2betax, zgc:92031

Protein level used designations for PPM1B

  • PP2C-beta
  • protein phosphatase 1B
  • protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform
  • protein phosphatase 2C isoform beta
  • protein phosphatase 2C-like protein
  • Protein phosphatase type 1B (formely 2C) Mg-dependent beta isoform
  • Protein phosphatase type 1B (formely 2C), Mg-dependent, beta isoform
  • protein phosphatase 1B, magnesium dependent, beta isoform
  • protein phosphatase type 2C beta
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