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PPP6C Products

(Protein Phosphatase 6, Catalytic Subunit (PPP6C))

Categories

This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. Splice variants encoding different protein isoforms exist. The pseudogene of this gene is located on chromosome X. [provided by RefSeq, Jul 2008].

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Featured PPP6C Categories

PPP6C Antibodies

High quality antibodies with extensive validation data.

PPP6C Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended PPP6C Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN6242920
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (2)
Cat. No. ABIN7169292
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN392922
Quantity 400 μL
Datasheet Datasheet

Recommended PPP6C ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6211660
Quantity 96 tests
Datasheet Datasheet

Recommended PPP6C Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1316091
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7420156
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3086324
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our PPP6C products

Williams, Filter, Blake-Hodek, Wadzinski, Fuda, Shalloway, Goldberg: "Greatwall-phosphorylated Endosulfine is both an inhibitor and a substrate of PP2A-B55 heterotrimers." in: eLife, Vol. 3, pp. e01695, (2014) (PubMed).

Shen, Wang, Sheng, Fei, Guo, Larner, Kong, Qiu, Mi: "Serine/threonine protein phosphatase 6 modulates the radiation sensitivity of glioblastoma." in: Cell death & disease, Vol. 2, pp. e241, (2011) (PubMed).

Douglas, Zhong, Ye, Moorhead, Xu, Lees-Miller: "Protein phosphatase 6 interacts with the DNA-dependent protein kinase catalytic subunit and dephosphorylates gamma-H2AX." in: Molecular and cellular biology, Vol. 30, Issue 6, pp. 1368-81, (2010) (PubMed).

Ivanov, Goparaju, Lopez, Zavadil, Toren-Haritan, Rosenwald, Hoshen, Chajut, Cohen, Pass: "Pro-tumorigenic effects of miR-31 loss in mesothelioma." in: The Journal of biological chemistry, Vol. 285, Issue 30, pp. 22809-17, (2010) (PubMed).

Zeng, Bastos, Barr, Gruneberg: "Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2." in: The Journal of cell biology, Vol. 191, Issue 7, pp. 1315-32, (2010) (PubMed).

Yang, Roe, Cliff, Williams, Ladbury, Cohen, Barford: "Molecular basis for TPR domain-mediated regulation of protein phosphatase 5." in: The EMBO journal, Vol. 24, Issue 1, pp. 1-10, (2005) (PubMed).

Huang, Shu, Easton, Harwood, Germain, Ichijo, Houghton: "Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity." in: The Journal of biological chemistry, Vol. 279, Issue 35, pp. 36490-6, (2004) (PubMed).

Zhou, Golden, Aragon, Honkanen: "Ser/Thr protein phosphatase 5 inactivates hypoxia-induced activation of an apoptosis signal-regulating kinase 1/MKK-4/JNK signaling cascade." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46595-605, (2004) (PubMed).

Synonyms and alternative names related to PPP6C

protein phosphatase 6 catalytic subunit (PPP6C), protein phosphatase 6, catalytic subunit (Ppp6c), protein phosphatase 6, catalytic subunit (ppp6c), protein phosphatase 6, catalytic subunit L homeolog (ppp6c.L), protein phosphatase 6 catalytic subunit (ppp6C), serine/threonine-protein phosphatase 6 catalytic subunit (Ppp6c), Protein phosphatase V (PpV), protein phosphatase 6 catalytic subunit (Ppp6c), 2310003C10Rik, CG12217, DDBDRAFT_0168786, DDBDRAFT_0185210, DDB_0168786, DDB_0185210, Dmel\\CG12217, DmPpV-6A, dPP6, MGC114734, PP6, pp6, PP6C, ppp6c, PPP6C, PPPV6A, PPV, Ppv, PPV 6A, zgc:56227

Protein level used designations for PPP6C

  • serine/threonine protein phosphatase catalytic subunit
  • serine/threonine-protein phosphatase 6 catalytic subunit
  • PP6C
  • PP-V
  • protein phosphatase V
  • protein phosphatase 6, catalytic subunit
  • serine/threonine-protein phosphatase 6 catalytic subunit-like
  • CG12217-PA
  • CG12217-PB
  • CG12217-PC
  • CG12217-PD
  • PpV-PA
  • PpV-PB
  • PpV-PC
  • PpV-PD
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