Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Profilin Products

(Profilin (PFN))
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG (By similarity). {ECO:0000250}.

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured Profilin Categories

Profilin Antibodies

High quality antibodies with extensive validation data.

Profilin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Profilin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Guinea Pig, Human, Rabbit
Application ICC, IHC, WB
Validations
  • (6)
  • (1)
Cat. No. ABIN1742559
Quantity 100 μg
Datasheet Datasheet
Reactivity Birch
Application ICC, IP, WB
Validations
  • (1)
Cat. No. ABIN1742560
Quantity 100 μg
Datasheet Datasheet
Reactivity Mercenaria (Clam)
Application ELISA, WB
Validations
Cat. No. ABIN7176863
Quantity 100 μg
Datasheet Datasheet

Recommended Profilin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2745816
Quantity 3 x 10 μg
Datasheet Datasheet
Reactivity Bombyx mori
Source Yeast
Validations
Cat. No. ABIN1635566
Quantity 1 mg
Datasheet Datasheet
Reactivity Branchiostoma belcheri
Source Yeast
Validations
Cat. No. ABIN1640941
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Profilin products

Lorente, Syriani, Morales: "Actin filaments at the leading edge of cancer cells are characterized by a high mobile fraction and turnover regulation by profilin I." in: PLoS ONE, Vol. 9, Issue 1, pp. e85817, (2014) (PubMed).

Giesemann, Schwarz, Nawrotzki, Berhörster, Rothkegel, Schlüter, Schrader, Schindelin, Mendel, Kirsch, Jockusch: "Complex formation between the postsynaptic scaffolding protein gephyrin, profilin, and Mena: a possible link to the microfilament system." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 23, Issue 23, pp. 8330-9, (2003) (PubMed).

Giesemann, Rathke-Hartlieb, Rothkegel, Bartsch, Buchmeier, Jockusch, Jockusch: "A role for polyproline motifs in the spinal muscular atrophy protein SMN. Profilins bind to and colocalize with smn in nuclear gems." in: The Journal of biological chemistry, Vol. 274, Issue 53, pp. 37908-14, (2000) (PubMed).

Janke, Schlüter, Jandrig, Theile, Kölble, Arnold, Grinstein, Schwartz, Estevéz-Schwarz, Schlag, Jockusch, Scherneck: "Suppression of tumorigenicity in breast cancer cells by the microfilament protein profilin 1." in: The Journal of experimental medicine, Vol. 191, Issue 10, pp. 1675-86, (2000) (PubMed).

Schlüter, Schleicher, Jockusch: "Effects of single amino acid substitutions in the actin-binding site on the biological activity of bovine profilin I." in: Journal of cell science, Vol. 111 ( Pt 22), pp. 3261-73, (1999) (PubMed).

Wiedemann, Giehl, Almo, Fedorov, Girvin, Steinberger, Rüdiger, Ortner, Sippl, Dolecek, Kraft, Jockusch, Valenta: "Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody." in: The Journal of biological chemistry, Vol. 271, Issue 47, pp. 29915-21, (1997) (PubMed).

Synonyms and alternative names related to Profilin

profilin (PFN), profilin (PRF), GB13380, LOC406154

Protein level used designations for Profilin

  • profilin
You are here:
Support