Streptolysin O Protein (SLO) (full length)
SLO
Origin: Streptococcus pyogenes
Host: Bacteria
Native
> 95 % (SDS-PAGE)
ELISA, WB
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- Target See all Streptolysin O (SLO) Proteins
- Streptolysin O (SLO)
- Protein Type
- Native
- Protein Characteristics
- full length
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Origin
- Streptococcus pyogenes
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Source
- Bacteria
- Application
- ELISA, Western Blotting (WB)
- Purification
- Purified from Streptococcus hemolyticus
- Purity
- > 95 % (SDS-PAGE)
- Top Product
- Discover our top product SLO Protein
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Streptolysin O (SLO) (Active) protein
SLO Origin: Streptococcus pyogenes Host: Escherichia coli (E. coli) Recombinant > 98 % by SDS-PAGE ELISA, WB, SDS Active
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- Comment
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Full length native Streptolysin O
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Repeated freezing and thawing is not recommended.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 ° C or -80 ° C.
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- Target
- Streptolysin O (SLO)
- Alternative Name
- Streptolysin O (SLO Products)
- Synonyms
- streptolysin O Protein, Streptolysin O Protein, Thiol-activated cytolysin Protein, slo Protein, M6_Spy0188 Protein
- Background
- Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation.
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