AG-2 (AA 21-175) protein (His tag)
Quick Overview for AG-2 (AA 21-175) protein (His tag) (ABIN1095972)
Target
Protein Type
Origin
Source
Purity
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Protein Characteristics
- AA 21-175
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Purification tag / Conjugate
- His tag
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Purpose
- Recombinant Human Anterior Gradient Protein 2 Homolog/AG-2/HPC8/AGR2 (C-6His)
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Sequence
- RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTELVDHHH HHH
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Characteristics
- Recombinant Human Anterior Gradient Protein 2 Homolog is produced by our Mammalian expression system and the target gene encoding Arg21-Leu175 is expressed with a 6His tag at the C-terminus.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 um filtered solution of 20 mM Tris-HCl, 200 mM NaCl, 10 % Glycerol, pH 8.0.
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Handling Advice
- minimize freeze-thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- AG-2
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Sub Type
- Fusionprotein
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Target Type
- Viral Protein
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Background
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Alternative Names: Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
Alternative Names: Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2 -
Molecular Weight
- 18.85 kDa
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UniProt
- O95994
Target
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