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AG-2 (AA 21-175) protein (His tag)

This Recombinant AG-2 protein is expressed in Human Cells.
Catalog No. ABIN1095972
$475.80
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Quick Overview for AG-2 (AA 21-175) protein (His tag) (ABIN1095972)

Target

AG-2

Protein Type

Recombinant

Origin

Human

Source

Human Cells

Purity

> 95 % as determined by reducing SDS-PAGE.
  • Protein Characteristics

    AA 21-175

    Purification tag / Conjugate

    His tag

    Purpose

    Recombinant Human Anterior Gradient Protein 2 Homolog/AG-2/HPC8/AGR2 (C-6His)

    Sequence

    RDTTVKPGAK KDTKDSRPKL PQTLSRGWGD QLIWTQTYEE ALYKSKTSNK PLMIIHHLDE CPHSQALKKV FAENKEIQKL AEQFVLLNLV YETTDKHLSP DGQYVPRIMF VDPSLTVRAD ITGRYSNRLY AYEPADTALL LDNMKKALKL LKTELVDHHH HHH

    Characteristics

    Recombinant Human Anterior Gradient Protein 2 Homolog is produced by our Mammalian expression system and the target gene encoding Arg21-Leu175 is expressed with a 6His tag at the C-terminus.

    Sterility

    0.2 μm filtered

    Endotoxin Level

    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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  • Restrictions

    For Research Use only
  • Format

    Liquid

    Reconstitution

    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Buffer

    Supplied as a 0.2 um filtered solution of 20 mM Tris-HCl, 200 mM NaCl, 10 % Glycerol, pH 8.0.

    Handling Advice

    minimize freeze-thaw cycles

    Storage

    -20 °C

    Storage Comment

    Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

    Expiry Date

    6 months
  • Target

    AG-2

    Sub Type

    Fusionprotein

    Target Type

    Viral Protein

    Background

    Alternative Names: Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor. Mature human AGR2 is 155 amino acids (aa) in length (aa 21 - 175). Cys81 is presumed to participate in intermolecular bond formation. Over aa 21 - 175, human AGR2 shares 94% aa identity with mouse AGR2.
    Alternative Names: Anterior Gradient Protein 2 Homolog, AG-2, hAG-2, HPC8, Secreted Cement Gland Protein XAG-2 Homolog, AGR2, AG2

    Molecular Weight

    18.85 kDa

    UniProt

    O95994
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