Coxsackie Adenovirus Receptor Protein (AA 20-217) (His tag)

Catalog No. ABIN1096455

This Recombinant Coxsackie Adenovirus Receptor protein is expressed in Human Cells.

Quick Overview for Coxsackie Adenovirus Receptor Protein (AA 20-217) (His tag) (ABIN1096455)

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 20-217

Purification tag / Conjugate: This Coxsackie Adenovirus Receptor protein is labelled with His tag.

Purpose: Recombinant Human Coxsackievirus and Adenovirus Receptor/CAR/CXADR (C-6His)

Sequence: LSITTPEEMI EKAKGETAYL PCKFTLSPED QGPLDIEWLI SPADNQKVDQ VIILYSGDKI YDDYYPDLKG RVHFTSNDLK SGDASINVTN LQLSDIGTYQ CKVKKAPGVA NKKIHLVVLV KPSGARCYVD GSEEIGSDFK IKCEPKEGSL PLQYEWQKLS DSQKMPTSWL AEMTSSVISV KNASSEYSGT YSCTVRNRVG SDQCLLRLNV VPPSNKAGVD HHHHHH

Characteristics: Recombinant Human Coxsackievirus and Adenovirus Receptor/CAR is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Leu20-Gly217) of Human CAR fused with a polyhistidine tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Coxsackie Adenovirus Receptor (CXADR) (Coxsackie Virus and Adenovirus Receptor (CXADR))

Alternative Name: cxadr

Sub Type: Fusionprotein

Background: Coxsackievirus and Adenovirus Receptor (CAR) belongs to the CTX family of the Ig superfamily. CXADR is a type I transmembrane glycoprotein and expressed in pancreas, brain, heart, small intestine, testis, prostate. It is a receptor that mediates gene transfer and also act as an adhesion molecule within junctional complexes, notably between epithelial cells lining body cavities and within myocardial intercalated discs. CXADR contains an extracellular domain, a transmembrane helix and a C-terminal intracellular domain. The C-terminal interacts with few cytoplasmic junctional proteins, microtubules and the actin cytoskeleton.
Alternative Names: Coxsackievirus and Adenovirus Receptor, CAR, hCAR, CVB3-Binding Protein, Coxsackievirus B-Adenovirus Receptor, HCVADR, CXADR, CAR

Molecular Weight: 25.08 kDa

UniProt: P78310

Pathways: Cell-Cell Junction Organization