FBP1 Protein (AA 2-338) (His tag)
-
- Target See all FBP1 Proteins
- FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 2-338
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This FBP1 protein is labelled with His tag.
- Purpose
- Recombinant Human Fructose-1,6-Bisphosphatase 1/FBPase 1 (E. coli, C-6His)
- Sequence
- ADQAPFDTDV NTLTRFVMEE GRKARGTGEL TQLLNSLCTA VKAISSAVRK AGIAHLYGIA GSTNVTGDQV KKLDVLSNDL VMNMLKSSFA TCVLVSEEDK HAIIVEPEKR GKYVVCFDPL DGSSNIDCLV SVGTIFGIYR KKSTDEPSEK DALQPGRNLV AAGYALYGSA TMLVLAMDCG VNCFMLDPAI GEFILVDKDV KIKKKGKIYS LNEGYARDFD PAVTEYIQRK KFPPDNSAPY GARYVGSMVA DVHRTLVYGG IFLYPANKKS PNGKLRLLYE CNPMAYVMEK AGGMATTGKE AVLDVIPTDI HQRAPVILGS PDDVLEFLKV YEKHSAQVEH HHHHH
- Characteristics
- Recombinant Human Fructose-1,6-Bisphosphatase 1/FBPase 1 is produced with our E. coli expression system. The target protein is expressed with sequence (Ala2-Gln338) of Human FBPase 1.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product FBP1 Protein
-
Fructose-1,6-Bisphosphatase 1 (FBP1) (AA 199-338) protein (His-IF2DI Tag)
FBP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses ELISA, WB
Fructose-1,6-Bisphosphatase 1 (FBP1) (AA 1-338) protein (His tag)FBP1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Fructose-1,6-Bisphosphatase 1 (FBP1) (AA 1-338) protein (GST tag)FBP1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 200 mM NaCl, 1 mM DTT, 1 mM EDTA, 20 % Glycerol, pH 8.0.
- Preservative
- Dithiothreitol (DTT)
- Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
-
Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
-
- Target
- FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))
- Alternative Name
- Fructose-1,6-Bisphosphatase 1/FBPase 1 (FBP1 Products)
- Background
-
Fructose-1,6-Bisphosphatase 1 (FBPase 1) is a member of the FBPase class 1 family. FBPase 1 is a gluconeogenesis regulatory protein, which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBPase 1 can assume an active R-state, or an inactive T-state. FBPase 1 deficiency is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis in newborn infants or young children. FBPase 1 coupled with phosphofructokinase (PFK) is involved in the metabolism of pancreatic islet cells.
Alternative Names: Fructose-1,6-Bisphosphatase 1, FBPase 1, D-Fructose-1,6-Bisphosphate 1-Phosphohydrolase 1, FBP1, FBP - Molecular Weight
- 37.89 kDa
- UniProt
- P09467
- Pathways
- Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport
-
