FBP1 Protein (His tag)

Catalog No. ABIN7319229

Product Details

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This FBP1 protein is labelled with His tag.

Purpose: Recombinant Human FBPase 1/FBP1 Protein (Human Cells, His Tag)

Sequence: Ala2-Gln338

Characteristics: Recombinant Human Fructose-1,6-Bisphosphatase 1 is produced by our Mammalian expression system and the target gene encoding Ala2-Gln338 is expressed with a 6His tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin Level: < 1.0 EU per μg as determined by the LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl,200 mM NaCl,1 mM DTT,10 % Glycerol, pH 8.0.

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Target Details

Target: FBP1 (Fructose-1,6-Bisphosphatase 1 (FBP1))

Alternative Name: FBPase 1/FBP1 (FBP1 Products)

Synonyms: FBP Protein, Fbp-2 Protein, Fbp2 Protein, Fbp3 Protein, FBP1 Protein, fbp2 Protein, Fdp Protein, CG10611 Protein, CG31692 Protein, Dmel\\CG31692 Protein, FbPase Protein, fbp1 Protein, cb598 Protein, fb57b01 Protein, zgc:64127 Protein, id:ibd1091 Protein, wu:fb17g10 Protein, wu:fb57b01 Protein, fdp Protein, xcc-b100_0105 Protein, fbp1l Protein, fk92h02 Protein, wu:fk92h02 Protein, zgc:64096 Protein, fbp Protein, fbp1.S Protein, fructose-bisphosphatase 1 Protein, fructose bisphosphatase 1 Protein, Fructose-1,6-bisphosphatase Protein, fructose-1,6-bisphosphatase Protein, fructose-1,6-bisphosphatase 1 Protein, fructose-bisphosphatase class I Protein, fructose-1,6-bisphosphatase 1b Protein, fbp Protein, fructose-1,6-bisphosphatase 1a Protein, fructose-bisphosphatase 1 L homeolog Protein, FBP1 Protein, Fbp1 Protein, fbp1 Protein, LOC100136618 Protein, RR_RS07410 Protein, fbp Protein, fbp1b Protein, fbp1a Protein, fbp1.L Protein

Background:

Background: Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis, gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.

Synonym: Fructose-1,6-bisphosphatase 1,D-fructose-1,6-bisphosphate 1-phosphohydrolase 1,FBP,FBPase 1

Molecular Weight: 37.8 kDa

UniProt: P09467

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Dicarboxylic Acid Transport