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IL17F Protein (Homodimer)

IL17F Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE. Func Active
Catalog No. ABIN1096909
  • Target See all IL17F Proteins
    IL17F (Interleukin 17F (IL17F))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    Homodimer
    Origin
    • 15
    • 10
    • 7
    • 2
    • 1
    Human
    Source
    • 13
    • 10
    • 4
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Application
    Functional Studies (Func)
    Purpose
    Recombinant Human Interleukin-17F/IL-17F
    Sequence
    MRKIPKVGHT FFQKPESCPP VPGGSMKLDI GIINENQRVS MSRNIESRST SPWNYTVTWD PNRYPSEVVQ AQCRNLGCIN AQGKEDISMN SVPIQQETLV VRRKHQGCSV SFQLEKVLVT VGCTCVTPVI HHVQ
    Characteristics
    Recombinant Human Interleukin-17F/IL-17F produced in E. coli is a disulfide-linked homodimer of 30.1 kDa, consisting of two non-glycosylated polypeptide chains with 134 amino acids each.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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    Discover our top product IL17F Protein
  • Comment

    Biological activity: ED50 is approximately 10 ng/ml as determined by the dose-dependent induction of IL-6 in NIH-3T3 cells.Specific Activity of 1.0 x 105 IU/mg

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in 500 mM Acetic Acid.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Expiry Date
    3 months
  • Target
    IL17F (Interleukin 17F (IL17F))
    Alternative Name
    il-17f (IL17F Products)
    Synonyms
    CANDF6 Protein, IL-17F Protein, ML-1 Protein, ML1 Protein, C87042 Protein, IL17F Protein, interleukin 17F Protein, IL17F Protein, Il17f Protein
    Background
    Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Today, IL-17 represents a family of structurally related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis.
    Alternative Names: Interleukin-17F, IL-17F, Cytokine ML-1, Interleukin-24, IL-24, IL17F, IL24
    Molecular Weight
    30.1 kDa
    UniProt
    Q96PD4
    Pathways
    Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity
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