Kallikrein 6 Protein (KLK6) (AA 17-244) (His tag)

Catalog No. ABIN1097017

Recombinant Kallikrein 6 protein expressed in Human Cells.

Quick Overview for Kallikrein 6 Protein (KLK6) (AA 17-244) (His tag) (ABIN1097017)

Target: Kallikrein 6 (KLK6)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 17-244

Purification tag / Conjugate: This Kallikrein 6 protein is labelled with His tag.

Purpose: Recombinant Human Kallikrein 6/KLK6/Neurosin (C-6His)

Sequence: EEQNKLVHGG PCDKTSHPYQ AALYTSGHLL CGGVLIHPLW VLTAAHCKKP NLQVFLGKHN LRQRESSQEQ SSVVRAVIHP DYDAASHDQD IMLLRLARPA KLSELIQPLP LERDCSANTT SCHILGWGKT ADGDFPDTIQ CAYIHLVSRE ECEHAYPGQI TQNMLCAGDE KYGKDSCQGD SGGPLVCGDH LRGLVSWGNI PCGSKEKPGV YTNVCRYTNW IQKTIQAKVD HHHHHH

Characteristics: Recombinant Human Kallikrein 6 is produced by our Mammalian expression system and the target gene encoding Glu17-Lys244 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 um filtered solution of 5 mM HCl, 150 mM NaCl.

Handling Advice: minimize freeze-thaw cycles

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: Kallikrein 6 (KLK6)

Alternative Name: neurosin

Sub Type: Fusionprotein

Background: Alternative Names: Kallikrein-6, Neurosin, Protease M, SP59, Serine Protease 18, Serine Protease 9, Zyme, KLK6, PRSS18, PRSS9Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen Kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
Alternative Names: Kallikrein-6, Neurosin, Protease M, SP59, Serine Protease 18, Serine Protease 9, Zyme, KLK6, PRSS18, PRSS9

Molecular Weight: 26.17 kDa

UniProt: Q92876

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling