LTBR Protein (AA 31-227) (His tag)

Catalog No. ABIN1097113

Recombinant LTBR protein expressed in HEK-293 Cells.

Quick Overview for LTBR Protein (AA 31-227) (His tag) (ABIN1097113)

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 31-227

Purification tag / Conjugate: This LTBR protein is labelled with His tag.

Purpose: Recombinant Human Lymphotoxin beta Receptor/LTBR (C-His)

Sequence: QAVPPYASEN QTCRDQEKEY YEPQHRICCS RCPPGTYVSA KCSRIRDTVC ATCAENSYNE HWNYLTICQL CRPCDPVMGL EEIAPCTSKR KTQCRCQPGM FCAAWALECT HCELLSDCPP GTEAELKDEV GKGNNHCVPC KAGHFQNTSS PSARCQPHTR CENQGLVEAA PGTAQSDTTC KNPLEPLPPE MSGTMLMVDH HHHHH

Characteristics: Recombinant Human Lymphotoxin beta Receptor is produced by our Mammalian expression system and the target gene encoding Gln31-Met227 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4

Storage: 4 °C,-20 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-5 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: LTBR (Lymphotoxin beta Receptor (TNFR Superfamily, Member 3) (LTBR))

Sub Type: Fusionprotein

Background: Alternative Names: Tumor Necrosis Factor Receptor Superfamily Member 3, Lymphotoxin-Beta Receptor, TumorNecrosis Factor C Receptor, Tumor Necrosis Factor Receptor 2-Related Protein, Tumor NecrosisFactor Receptor Type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, TNFRSF3Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition, LTBR can lead to the release of the cytokine interleukin 8.
Alternative Names: Tumor Necrosis Factor Receptor Superfamily Member 3, Lymphotoxin-Beta Receptor, Tumor Necrosis Factor C Receptor, Tumor Necrosis Factor Receptor 2-Related Protein, Tumor Necrosis Factor Receptor Type III, TNF-RIII, TNFR-III, LTBR, D12S370, TNFCR, TNFR3, T

Molecular Weight: 22.79 kDa

UniProt: P36941

Pathways: NF-kappaB Signaling