NPTN Protein (AA 29-220) (His tag)

Catalog No. ABIN1097225

Recombinant NPTN protein expressed in Human Cells.

Quick Overview for NPTN Protein (AA 29-220) (His tag) (ABIN1097225)

Target: NPTN (Neuroplastin (NPTN))

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 29-220

Purification tag / Conjugate: This NPTN protein is labelled with His tag.

Purpose: Recombinant Human Neuroplastin/NPTN (C-6His)

Sequence: QNEPRIVTSE EVIIRDSPVL PVTLQCNLTS SSHTLTYSYW TKNGVELSAT RKNASNMEYR INKPRAEDSG EYHCVYHFVS APKANATIEV KAAPDITGHK RSENKNEGQD ATMYCKSVGY PHPDWIWRKK ENGMPMDIVN TSGRFFIINK ENYTELNIVN LQITEDPGEY ECNATNAIGS ASVVTVLRVR SHVDHHHHHH

Characteristics: Recombinant Human Neuroplastin is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Gln29-His220) of Human NPTN fused with a polyhistidine tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: NPTN (Neuroplastin (NPTN))

Alternative Name: neuroplastin

Sub Type: Fusionprotein

Background: Neuroplastin is a 52-57 kDa member of the Ig-superfamily. Neuroplastin likely serves as a cell adhesion molecule, and is widely expressed in multiple tissues. Human Neuroplastin is 282 amino acids in length. Human Neuroplastin is a type I transmembrane glycoprotein that contions two Ig-like domains (aa 32-119 and 122-213) and a 38 aa cytoplasmic region (aa 245-282).
Alternative Names: Neuroplastin, Stromal Cell-Derived Receptor 1, SDR-1, NPTN, SDFR1, SDR1

Molecular Weight: 22.69 kDa

UniProt: Q9Y639

Pathways: Regulation of long-term Neuronal Synaptic Plasticity