NOL3 Protein (AA 1-208)
Quick Overview for NOL3 Protein (AA 1-208) (ABIN1097254)
Target
See all NOL3 ProteinsProtein Type
Origin
Source
Purity
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Protein Characteristics
- AA 1-208
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Purpose
- Recombinant Human Nucleolar Protein 3/NOL3 (His)
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Sequence
- MGNAQERPSE TIDRERKRLV ETLQADSGLL LDALLARGVL TGPEYEALDA LPDAERRVRR LLLLVQGKGE AACQELLRCA QRTAGAPDPA WDWQHVGPGY RDRSYDPPCP GHWTPEAPGS GTTCPGLPRA SDPDEAGGPE GSEAVQSGTP EEPEPELEAE ASKEAEPEPE PEPELEPEAE AEPEPELEPE PDPEPEPDFE ERDESEDS
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Characteristics
- Recombinant Human Nucleolar Protein 3 is produced by our E.coli expression system and the target gene encoding Met1-Ser208 is expressed.
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Sterility
- 0.2 μm filtered
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Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. -
Buffer
- Supplied as a 0.2 um filtered solution of 25 mM Tris-HCl, 1 mM DTT, 1 mM EDTA, 2 mM β-ME, 20 % Glycerol, pH 7.5.
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Preservative
- Dithiothreitol (DTT)
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Precaution of Use
- This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- minimize freeze-thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
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Expiry Date
- 6 months
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- NOL3 (Nucleolar Protein 3 (Apoptosis Repressor with CARD Domain) (NOL3))
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Alternative Name
- Nucleolar Protein 3/NOL3
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Background
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Alternative Names: Nucleolar Protein 3, Apoptosis Repressor With CARD, Muscle-Enriched Cytoplasmic Protein, Myp, Nucleolar Protein of 30 kDa, Nop30Recombinant Human Nucleolar Protein 3/NOL3 (HIS-tagged) is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ser208) of Human NOL3.
Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in RNA splicing.Isoform 2 may inhibit apoptosis.It has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. -
Molecular Weight
- 22.63 kDa
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UniProt
- O60936
Target
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