SCGB3A2 Protein (AA 22-93)

Catalog No. ABIN1097757

This Recombinant SCGB3A2 protein is expressed in Escherichia coli (E. coli).

Quick Overview for SCGB3A2 Protein (AA 22-93) (ABIN1097757)

Target: SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 22-93

Purpose: Recombinant Human Uteroglobin-Related Protein 1/UGRP1

Sequence: FLINKVPLPV DKLAPLPLDN ILPFMDPLKL LLKTLGISVE HLVEGLRKCV NELGPEASEA VKKLLEALSH LV

Characteristics: Recombinant Human Uteroglobin-Related Protein 1/UGRP1 is produced by our E. coli expression system. The target protein is expressed with sequence (Phe22-Val93) of Human UGRP1.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))

Alternative Name: ugrp1

Background: Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 interacts with the macrophage scavenger receptor with collagenous structure which is expressed by alveolar macrophages in the lung. It have suggested that UGRP1 may be involved in inflammation and pathogen clearance in the lung by binding to its receptor.
Alternative Names: Secretoglobin Family 3A Member 2, Pneumo Secretory Protein 1, PnSP-1, Uteroglobin-Related Protein 1, SCGB3A2, PNSP1, UGRP1

Molecular Weight: 7.9 kDa

UniProt: Q96PL1