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SCGB3A2 Protein

SCGB3A2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7319165
  • Target See all SCGB3A2 Proteins
    SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    • 2
    Human
    Source
    • 5
    • 2
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human UGRP1 Protein
    Sequence
    Phe22-Val93
    Characteristics
    Recombinant Human Uteroglobin-Related Protein 1 is produced by our E.coli expression system and the target gene encoding Phe22-Val93 is expressed.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Please refer to the printed manual for detailed information.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    SCGB3A2 (Secretoglobin, Family 3A, Member 2 (SCGB3A2))
    Alternative Name
    UGRP1 (SCGB3A2 Products)
    Synonyms
    SCGB3A2 Protein, LU103 Protein, PNSP1 Protein, UGRP1 Protein, pnSP-1 Protein, LuLeu1 Protein, Pnsp1 Protein, Utgrp1 Protein, secretoglobin family 3A member 2 Protein, secretoglobin, family 3A, member 2 Protein, SCGB3A2 Protein, Scgb3a2 Protein
    Background

    Background: Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amino acid sequence similarity with uteroglobin. UGRP1 is expressed predominantly in the lung and low levels of expression are detected in the thyroid. Expression of UGRP1 in lung epithelial cells is enhanced by IL-10 and decreased through the activities of IL-9 and IL-5. UGRP1 interacts with the macrophage scavenger receptor with collagenous structure which is expressed by alveolar macrophages in the lung. It have suggested that UGRP1 may be involved in inflammation and pathogen clearance in the lung by binding to its receptor.

    Synonym: Secretoglobin Family 3A Member 2, Pneumo Secretory Protein 1, PnSP-1, Uteroglobin-Related Protein 1, SCGB3A2, PNSP1, UGRP1

    Molecular Weight
    7.9 kDa
    UniProt
    Q96PL1
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