PLK3 Protein (AA 1-646) (GST tag)

Catalog No. ABIN1315440

This Recombinant PLK3 protein is expressed in Wheat germ and has been mentioned in 1 publication.

Quick Overview for PLK3 Protein (AA 1-646) (GST tag) (ABIN1315440)

Target: PLK3 (Polo-Like Kinase 3 (PLK3))

Protein Type: Recombinant

Origin: Human

Source: Wheat germ

Application: ELISA, Western Blotting (WB), Affinity Purification (AP), Antibody Array (AA)

Product Details

Protein Characteristics: AA 1-646

Purification tag / Conjugate: This PLK3 protein is labelled with GST tag.

Purpose: PLK3 (Human) Recombinant Protein (P01)

Sequence: MEPAAGFLSP RPFQRAAAAP APPAGPGPPP SALRGPELEM LAGLPTSDPG RLITDPRSGR TYLKGRLLGK GGFARCYEAT DTETGSAYAV KVIPQSRVAK PHQREKILNE IELHRDLQHR HIVRFSHHFE DADNIYIFLE LCSRKSLAHI WKARHTLLEP EVRYYLRQIL SGLKYLHQRG ILHRDLKLGN FFITENMELK VGDFGLAARL EPPEQRKKTI CGTPNYVAPE VLLRQGHGPE ADVWSLGCVM YTLLCGSPPF ETADLKETYR CIKQVHYTLP ASLSLPARQL LAAILRASPR DRPSIDQILR HDFFTKGYTP DRLPISSCVT VPDLTPPNPA RSLFAKVTKS LFGRKKKSKN HAQERDEVSG LVSGLMRTSV GHQDARPEAP AASGPAPVSL VETAPEDSSP RGTLASSGDG FEEGLTVATV VESALCALRN CIAFMPPAEQ NPAPLAQPEP LVWVSKWVDY SNKFGFGYQL SSRRVAVLFN DGTHMALSAN RKTVHYNPTS TKHFSFSVGA VPRALQPQLG ILRYFASYME QHLMKGGDLP SVEEVEVPAP PLLLQWVKTD QALLMLFSDG TVQVNFYGDH TKLILSGWEP LLVTFVARNR SACTYLASHL RQLGCSPDLR QRLRYALRLL RDRSPA

Characteristics: Human PLK3 full-length ORF ( NP_004064.2, 1 a.a. - 646 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Chen, Huang, Liu, Xu, Jiang: "Design, synthesis, and evaluation of non-ATP-competitive small-molecule Polo-like kinase 1 (Plk1) inhibitors." in: Archiv der Pharmazie, Vol. 348, Issue 1, pp. 2-9, (2015) (PubMed).

Target Details

Target: PLK3 (Polo-Like Kinase 3 (PLK3))

Alternative Name: PLK3

Background: Full Gene Name: polo-like kinase 3 (Drosophila)
Synonyms: CNK,FNK,PRK

Gene ID: 1263

NCBI Accession: NM_004073

Pathways: Regulation of long-term Neuronal Synaptic Plasticity