SMN2 Protein (AA 1-282) (GST tag)

Catalog No. ABIN1320680

This Recombinant SMN2 protein is expressed in Wheat germ and has been mentioned in 1 publication.

Quick Overview for SMN2 Protein (AA 1-282) (GST tag) (ABIN1320680)

Target: SMN2 (Survival of Motor Neuron 2, Centromeric (SMN2))

Protein Type: Recombinant

Origin: Human

Source: Wheat germ

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Product Details

Protein Characteristics: AA 1-282

Purification tag / Conjugate: This SMN2 protein is labelled with GST tag.

Purpose: SMN2 (Human) Recombinant Protein (P02)

Sequence: MAMSSGGSGG GVPEQEDSVL FRRGTGQSDD SDIWDDTALI KAYDKAVASF KHALKNGDIC ETSGKPKTTP KRKPAKKNKS QKKNTAASLQ QWKVGDKCSA IWSEDGCIYP ATIASIDFKR ETCVVVYTGY GNREEQNLSD LLSPICEVAN NIEQNAQENE NESQVSTDES ENSRSPGNKS DNIKPKSAPW NSFLPPPPPM PGPRLGPGKP GLKFNGPPPP PPPPPPHLLS CWLPPFPSGP PIIPPPPPIC PDSLDDADAL GSMLISWYMS GYHTGYYMEM LA

Characteristics: Human SMN2 full-length ORF ( AAH00908, 1 a.a. - 282 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Cucchiarini, Madry, Terwilliger: "Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis." in: Journal of cellular and molecular medicine, Vol. 18, Issue 1, pp. 115-24, (2013) (PubMed).

Target Details

Target: SMN2 (Survival of Motor Neuron 2, Centromeric (SMN2))

Alternative Name: SMN2

Background: Full Gene Name: survival of motor neuron 2, centromeric
Synonyms: BCD541,C-BCD541,FLJ76644,MGC20996,MGC5208,SMNC

Gene ID: 6607

Pathways: Ribonucleoprotein Complex Subunit Organization