SOCS2 Protein (AA 1-198) (GST tag)

Catalog No. ABIN1320927

Recombinant SOCS2 protein expressed in Wheat germ and has been mentioned in 1 publication.

Quick Overview for SOCS2 Protein (AA 1-198) (GST tag) (ABIN1320927)

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Protein Type: Recombinant

Origin: Human

Source: Wheat germ

Application: Western Blotting (WB), ELISA, Affinity Purification (AP), Antibody Array (AA)

Product Details

Protein Characteristics: AA 1-198

Purification tag / Conjugate: This SOCS2 protein is labelled with GST tag.

Purpose: SOCS2 (Human) Recombinant Protein (P01)

Sequence: MTLRCLEPSG NGGEGTRSQW GTAGSAEEPS PQAARLAKAL RELGQTGWYW GSMTVNEAKE KLKEAPEGTF LIRDSSHSDY LLTISVKTSA GPTNLRIEYQ DGKFRLDSII CVKSKLKQFD SVVHLIDYYV QMCKDKRTGP EAPRNGTVHL YLTKPLYTSA PSLQHLCRLT INKCTGAIWG LPLPTRLKDY LEEYKFQV

Characteristics: Human SOCS2 full-length ORF ( NP_003868.1, 1 a.a. - 198 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Sen, Peng, Woods, Wistuba, Bell, El-Naggar, Lai, Johnson: "STAT5A-mediated SOCS2 expression regulates Jak2 and STAT3 activity following c-Src inhibition in head and neck squamous carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 1, pp. 127-39, (2012) (PubMed).

Target Details

Target: SOCS2 (Suppressor of Cytokine Signaling 2 (SOCS2))

Alternative Name: SOCS2

Background: Gene: suppressor of cytokine signaling 2
Synonyms: CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2

Gene ID: 8835

NCBI Accession: NM_003877

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus