RECQL2 Protein (AA 1322-1432) (GST tag)
Quick Overview for RECQL2 Protein (AA 1322-1432) (GST tag) (ABIN1325380)
Target
Protein Type
Origin
Source
Application
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Protein Characteristics
- AA 1322-1432
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Purification tag / Conjugate
- This RECQL2 protein is labelled with GST tag.
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Purpose
- WRN (Human) Recombinant Protein (Q01)
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Sequence
- NPPVNSDMSK ISLIRMLAPE NIDTYLIHMA IEILKHGPDS GLQPSCDVNK RRCFPGSEEI CSSSKRSKEE VGINTETSSA ERKRRLPVWF AKGSDTSKKL MDKTKRGGLF S
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Characteristics
- Human WRN partial ORF ( NP_000544, 1322 a.a. - 1432 a.a.) recombinant protein with GST-tag at N-terminal.
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Purification
- in vitro wheat germ expression system
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -80 °C
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Storage Comment
- Best use within three months from the date of receipt of this protein.
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: "WRN protein as a novel erythroblast immunohistochemical marker with applications for the diagnosis of Werner syndrome." in: Virchows Archiv : an international journal of pathology, Vol. 466, Issue 3, pp. 343-50, (2015) (PubMed).
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- RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))
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Alternative Name
- WRN
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Background
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Gene: Werner syndrome
Synonyms: DKFZp686C2056, RECQ3, RECQL2, RECQL3 -
Gene ID
- 7486
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NCBI Accession
- NM_000553
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Pathways
- DNA Damage Repair
Target
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