Contactin 6 Protein (CNTN6) (AA 1-999) (Fc Tag)

Catalog No. ABIN1344107

This Recombinant Contactin 6 protein is produced in HEK-293 Cells.

Quick Overview for Contactin 6 Protein (CNTN6) (AA 1-999) (Fc Tag) (ABIN1344107)

Target: Contactin 6 (CNTN6)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293 Cells

Application: SDS-PAGE (SDS)

Purity: >90 % (SDS-PAGE)

Product Details

Protein Characteristics: AA 1-999

Purification tag / Conjugate: This Contactin 6 protein is labelled with Fc Tag.

Purpose: Contactin-6 (human):Fc (human) (rec.)

Cross-Reactivity: Human

Characteristics: Human contactin-6 (aa 1-999) is fused at the C-terminus to the Fc portion of human IgG.

Sterility: Sterile filtered

Endotoxin Level: <0.1EU/μg purified protein (LAL test).

Biological Activity Comment: Induces Hes-1 in 3T3L-1 cells.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.2μm-filtered solution in PBS.

Handling Advice: After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.

Storage: 4 °C,-20 °C

Storage Comment:

Short Term Storage: +4°C

Long Term Storage: -20°C

Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

Expiry Date: 6 months

Target Details

Target: Contactin 6 (CNTN6)

Alternative Name: Contactin-6

Background:

Neural Recognition Molecule NB-3, CNTN6

Contactin-6 is a member of the contactins, which mediate cell surface interactions during nervous system development. Contactin-6 has a key role in the formation of glutamatergic, but not GABAergic, synapses during postnatal development of the hippocampal formation as well as the cerebellum. It is involved in oligodendrocytes generation by acting as a ligand of Notch1. It is also involved in motor coordination.

Molecular Weight: ~150kDa (SDS-PAGE)

UniProt: Q9UQ52