RBP4 Protein (AA 19-201) (DYKDDDDK Tag)
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- Target See all RBP4 Proteins
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-201
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RBP4 protein is labelled with DYKDDDDK Tag.
- Application
- SDS-PAGE (SDS)
- Purpose
- RBP4 (human) (rec.)
- Cross-Reactivity
- Human
- Characteristics
- Human RBP4 (aa 19-201) is fused at the N-terminus to a FLAG®-tag.
- Purity
- >90 % (SDS-PAGE)
- Sterility
- Sterile filtered
- Endotoxin Level
- <0.1EU/μg purified protein (LAL test).
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.3 mg/mL
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.2.
- Handling Advice
- After opening, prepare aliquots and store at -20 °C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap.
- Storage
- 4 °C,-20 °C
- Storage Comment
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Short Term Storage: +4°C
Long Term Storage: -20°C
Use & Stability: Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
- Expiry Date
- 6 months
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- Target
- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
- Alternative Name
- RBP4 (RBP4 Products)
- Background
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Retinol Binding Protein 4
Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
- Molecular Weight
- ~23kDa (SDS-PAGE)
- UniProt
- P02753
- Pathways
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
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