Dynamin 1-Like Protein (DNM1L) (AA 1-710) (GST tag)

Catalog No. ABIN1351855

This Recombinant Dynamin 1-Like protein is produced in Wheat germ. There are 4 publications available.

Quick Overview for Dynamin 1-Like Protein (DNM1L) (AA 1-710) (GST tag) (ABIN1351855)

Target: Dynamin 1-Like (DNM1L)

Protein Type: Recombinant

Origin: Human

Source: Wheat germ

Application: Affinity Purification (AP), Antibody Array (AA), ELISA, Western Blotting (WB)

Product Details

Protein Characteristics: AA 1-710

Purification tag / Conjugate: This Dynamin 1-Like protein is labelled with GST tag.

Purpose: DNM1L (Human) Recombinant Protein (P01)

Sequence: MEALIPVINK LQDVFNTVGA DIIQLPQIVV VGTQSSGKSS VLESLVGRDL LPRGTGIVTR RPLILQLVHV SQEDKRKTTG EENGVEAEEW GKFLHTKNKL YTDFDEIRQE IENETERISG NNKGVSPEPI HLKIFSPNVV NLTLVDLPGM TKVPVGDQPK DIELQIRELI LRFISNPNSI ILAVTAANTD MATSEALKIS REVDPDGRRT LAVITKLDLM DAGTDAMDVL MGRVIPVKLG IIGVVNRSQL DINNKKSVTD SIRDEYAFLQ KKYPSLANRN GTKYLARTLN RLLMHHIRDC LPELKTRINV LAAQYQSLLN SYGEPVDDKS ATLLQLITKF ATEYCNTIEG TAKYIETSEL CGGARICYIF HETFGRTLES VDPLGGLNTI DILTAIRNAT GPRPALFVPE VSFELLVKRQ IKRLEEPSLR CVELVHEEMQ RIIQHCSNYS TQELLRFPKL HDAIVEVVTC LLRKRLPVTN EMVHNLVAIE LAYINTKHPD FADACGLMNN NIEEQRRNRL ARELPSAVSR DKLIQDSRRE TKNVASGGGG VGDGVQEPTT GNWRGMLKTS KAEELLAEEK SKPIPIMPAS PQKGHAVNLL DVPVPVARKL SAREQRDCEV IERLIKSYFL IVRKNIQDSV PKAVMHFLVN HVKDTLQSEL VGQLYKSSLL DDLLTESEDM AQRRKEAADM LKALQGASQI IAEIRETHLW

Characteristics: Human DNM1L full-length ORF ( AAH24590.1, 1 a.a. - 710 a.a.) recombinant protein with GST-tag at N-terminal.

Purification: in vitro wheat germ expression system

Application Details

Application Notes: Suggested Applications*:elisa,antibody array,western blotting,affinity purification
*We do not guarantee this product working for suggested applications.
Optimal working dilution should be determined by the investigator.

Comment:

Preparation method: in vitro, wheat germ expression system
Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

Restrictions: For Research Use only

Handling

Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -80 °C

Storage Comment: Best use within three months from the date of receipt of this protein.

References

Qi, Qvit, Su, Mochly-Rosen: "A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity." in: Journal of cell science, Vol. 126, Issue Pt 3, pp. 789-802, (2013) (PubMed).

Su, Qi: "Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation." in: Human molecular genetics, Vol. 22, Issue 22, pp. 4545-61, (2013) (PubMed).

Guo, Disatnik, Monbureau, Shamloo, Mochly-Rosen, Qi: "Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration." in: The Journal of clinical investigation, Vol. 123, Issue 12, pp. 5371-88, (2013) (PubMed).

Qi, Disatnik, Shen, Sobel, Mochly-Rosen: "Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo." in: Molecular biology of the cell, Vol. 22, Issue 2, pp. 256-65, (2011) (PubMed).

Target Details

Target: Dynamin 1-Like (DNM1L)

Alternative Name: DNM1L

Background: Full Gene Name: dynamin 1-like
Synonyms: DLP1,DRP1,DVLP,DYMPLE,DYNIV-11,FLJ41912,HDYNIV,VPS1

Gene ID: 10059