ERCC2 Protein (AA 1-405) (GST tag)
(1 reference)Quick Overview for ERCC2 Protein (AA 1-405) (GST tag) (ABIN1353031)
Target
See all ERCC2 ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- AA 1-405
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Purification tag / Conjugate
- This ERCC2 protein is labelled with GST tag.
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Purpose
- ERCC2 (Human) Recombinant Protein (P01)
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Sequence
- MRELKRTLDA KGHGVLEMPS GTGKTVSLLA LIMAYQRAYP LEVTKLIYCS RTVPEIEKVI EELRKLLNFY EKQEGEKLPF LGLALSSRKN LCIHPEVTPL RFGKDVDGKC HSLTASYVRA QYQHDTSLPH CRFYEEFDAH GREVPLPAGI YNLDDLKALG RRQGWCPYFL ARYSILHANV VVYSYHYLLD PKIADLVSKE LARKAVVVFD EAHNIDNVCI DSMSVNLTRR TLDRCQGNLE TLQKTVLRIK ETDEQRLRDE YRRLVEGLRE ASAARETDAH LANPVLPDEV LQEAVPGSIR TAEHFLGFLR RLLEYVKWRL RVQHVVQESP PAFLSGLAQR VCIQRKPLRF CAERLRSLLH TLEITDLADF SPLTLLANFA TLVSTYAKGQ AQHCGSSRNQ KRSHP
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Characteristics
- Human ERCC2 full-length ORF ( AAH08346, 1 a.a. - 405 a.a.) recombinant protein with GST-tag at N-terminal.
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Purification
- in vitro wheat germ expression system
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Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2) (AA 1-760) protein (His tag)
custom-made ERCC2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2) (AA 1-760) protein (His tag)custom-made ERCC2 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.
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Handling Advice
- Aliquot to avoid repeated freezing and thawing.
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Storage
- -80 °C
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Storage Comment
- Best use within three months from the date of receipt of this protein.
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: "Cadmium inhibits non-homologous end-joining and over-activates the MRE11-dependent repair pathway." in: Mutation research, Vol. 654, Issue 1, pp. 13-21, (2008) (PubMed).
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- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
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Alternative Name
- ERCC2
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Background
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Gene: excision repair cross-complementing rodent repair deficiency, complementation group 2
Synonyms: COFS2, EM9, MGC102762, MGC126218, MGC126219, TTD, XPD -
Gene ID
- 2068
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Pathways
- DNA Damage Repair
Target
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