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FOXO3 Protein (AA 1-673) (GST tag)

Recombinant FOXO3 protein expressed in Wheat germ and has been mentioned in 1 publication.
Catalog No. ABIN1354383

Quick Overview for FOXO3 Protein (AA 1-673) (GST tag) (ABIN1354383)

Target

See all FOXO3 Proteins
FOXO3 (Forkhead Box O3 (FOXO3))

Protein Type

Recombinant

Origin

  • 9
  • 4
Human

Source

  • 6
  • 4
  • 2
  • 1
Wheat germ

Application

Western Blotting (WB), ELISA, Antibody Array (AA), Affinity Purification (AP)
  • Protein Characteristics

    AA 1-673

    Purification tag / Conjugate

    This FOXO3 protein is labelled with GST tag.

    Purpose

    FOXO3 (Human) Recombinant Protein (P01)

    Sequence

    MAEAPASPAP LSPLEVELDP EFEPQSRPRS CTWPLQRPEL QASPAKPSGE TAADSMIPEE EDDEDDEDGG GRAGSAMAIG GGGGSGTLGS GLLLEDSARV LAPGGQDPGS GPATAAGGLS GGTQALLQPQ QPLPPPQPGA AGGSGQPRKC SSRRNAWGNL SYADLITRAI ESSPDKRLTL SQIYEWMVRC VPYFKDKGDS NSSAGWKNSI RHNLSLHSRF MRVQNEGTGK SSWWIINPDG GKSGKAPRRR AVSMDNSNKY TKSRGRAAKK KAALQTAPES ADDSPSQLSK WPGSPTSRSS DELDAWTDFR SRTNSNASTV SGRLSPIMAS TELDEVQDDD APLSPMLYSS SASLSPSVSK PCTVELPRLT DMAGTMNLND GLTENLMDDL LDNITLPPSQ PSPTGGLMQR SSSFPYTTKG SGLGSPTSSF NSTVFGPSSL NSLRQSPMQT IQENKPATFS SMSHYGNQTL QDLLTSDSLS HSDVMMTQSD PLMSQASTAV SAQNSRRNVM LRNDPMMSFA AQPNQGSLVN QNLLHHQHQT QGALGGSRAL SNSVSNMGLS ESSSLGSAKH QQQSPVSQSM QTLSDSLSGS SLYSTSANLP VMGHEKFPSD LDLDMFNGSL ECDMESIIRS ELMDADGLDF NFDSLISTQN VVGLNVGNFT GAKQASSQSW VPG

    Characteristics

    Human FOXO3 full-length ORF ( AAH20227.1, 1 a.a. - 673 a.a.) recombinant protein with GST-tag at N-terminal.

    Purification

    in vitro wheat germ expression system
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  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Preparation method: in vitro, wheat germ expression system
    Product Quality tested by: 12.5% SDS-PAGE Stained with Coomassie Blue.

    Restrictions

    For Research Use only
  • Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH =8.0 in the elution buffer.

    Handling Advice

    Aliquot to avoid repeated freezing and thawing.

    Storage

    -80 °C

    Storage Comment

    Best use within three months from the date of receipt of this protein.
  • Lützner, Kalbacher, Krones-Herzig, Rösl: "FOXO3 is a glucocorticoid receptor target and regulates LKB1 and its own expression based on cellular AMP levels via a positive autoregulatory loop." in: PLoS ONE, Vol. 7, Issue 7, pp. e42166, (2012) (PubMed).

  • Target

    FOXO3 (Forkhead Box O3 (FOXO3))

    Alternative Name

    FOXO3

    Background

    Full Gene Name: forkhead box O3
    Synonyms: AF6q21,DKFZp781A0677,FKHRL1,FKHRL1P2,FOXO2,FOXO3A,MGC12739,MGC31925

    Gene ID

    2309

    Pathways

    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis
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