HSD11B2 Protein (AA 1-404) (His tag)

Catalog No. ABIN1461110

Product Details

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Protein Type: Recombinant

Protein Characteristics: AA 1-404

Origin: Cow

Source: Yeast

Purification tag / Conjugate: This HSD11B2 protein is labelled with His tag.

Application: ELISA

Sequence: MESWPWPSGG AWLLVPARAL LQLLRADLRL GRPLLAALAL LAALDWLCQR LLPPLAALAV LAATGWIVLS RLARPQRLPV ATRAVLITGC DSGFGNATAK KLDTMGFTVL ATVLDLNSPG ALELRACCSS RLKLLQMDLT KPGDISRVLE FTKVHTPSTG LWGLVNNAGQ NIFVADAELC PVATFRTCME VNFFGALEMT KGLLPLLRRS SGRIVTVSSP AGDMPFPCLA AYGTSKAALA LLMGNFSCEL LPWGVKVSII QPACFKTESV KDVHQWEERK QQLLATLPQE LLQAYGEDYI EHLNGQFLHS LSQALPDLSP VVDAITDALL AAQPLRRYYP GHGLGLIYFI HYYLPEGLRQ RFLQSFFISP YVPRALQAGQ PGLTSARDIA QDQGPRPDPS PTAQ

Specificity: Bos taurus (Bovine)

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: > 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C, for extended storage, conserve at -20 °C or -80 °C.

Target Details

Target: HSD11B2 (Hydroxysteroid (11-Beta) Dehydrogenase 2 (HSD11B2))

Alternative Name: Corticosteroid 11-beta-dehydrogenase isozyme 2 (HSD11B2) (HSD11B2 Products)

Synonyms: MGC81883 Protein, 11-HSD2 Protein, AME Protein, AME1 Protein, HSD11K Protein, HSD2 Protein, SDR9C3 Protein, 11HSD2 Protein, HSD11B2 Protein, hydroxysteroid (11-beta) dehydrogenase 2 L homeolog Protein, hydroxysteroid 11-beta dehydrogenase 2 Protein, hsd11b2.L Protein, HSD11B2 Protein, Hsd11b2 Protein

Background: Recommended name: Corticosteroid 11-beta-dehydrogenase isozyme 2.
EC= 1.1.1.-.
Alternative name(s): 11-beta-hydroxysteroid dehydrogenase type 2.
Short name= 11-DH2.
Short name= 11-beta-HSD2 NAD-dependent 11-beta-hydroxysteroid dehydrogenase

UniProt: O77667

Pathways: Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones