SRY Protein

Catalog No. ABIN1589734

Recombinant SRY protein expressed in Escherichia coli (E. coli).

Quick Overview for SRY Protein (ABIN1589734)

Target: SRY (Sex Determining Region Y (SRY))

Protein Type: Recombinant

Origin: Cow

Source: Escherichia coli (E. coli)

Purity: > 90 % by SDS-PAGE

Product Details

Purpose: Recombinant Bovine SRY Protein

Sequence: MFRVLNDDVY SPAVVQQQTT LAFRKDSSLC TDSHSANDQC ERGEHVRESS QDHVKRPMNA FIVWSRERRR KVALENPKMK NSDISKQLGY EWKRLTDAEK RPFFEEAQRL LAIHRDKYPG YKYRPRRRAK RPQKSLPADS SILCNPMHVE TLHPFTYRDG CAKTTYSQME SQLSRSQSVI ITNSLLQKEH HSSWTSLGHN KVTLATRISA DFPCNKSLEP GLSCAYFQYL E

Characteristics: Length (aa):231

Application Details

Comment:

Cytokines & Growth Factors

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: PBS,Centrifuge vial prior to opening. Bovine SRY should be reconstituted in PBS to a concentration of 0.1 mg/mL. This solution can be diluted in water or other buffered solutions.

Buffer: water

Handling Advice: Centrifuge vial prior to opening

Storage: -20 °C

Storage Comment: The lyophilized powder although stable at room temperature for 3 weeks, is best stored desiccated at -20°C. Reconstituted bo SRY should be stored in working aliquots at -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).

Expiry Date: Unlimited (if stored properly)

Target Details

Target: SRY (Sex Determining Region Y (SRY))

Alternative Name: SRY

Background:

Synonyms: Sex-determining region Y protein, Testis-determining factor

Description: The ""Sex determining region of Y-Gen"" (SRY), known as SRY gene, is coding for a transkription factor (TDF for Testis-determining factor). It belongs to the protein family of DNA binding-proteins. The SRY gene is beside other genes used for the determination of the sex in human as well as other mammals. Most mammals have for this purpose a further gene, UBE1. In humans SRY is normally located on the short arm of the Y chromosome. Accordingly, people who possess this chromosome with the corresponding gene, normally have a male phenotype. It does not matter how many copies of the X chromosome are present, even people with a multiple X chromosome (Klinefelter's syndrome) have this. The protein encoded by the gene Testis-determining factor controls the development of male sex

Molecular Weight: 26.8 kDa

Gene ID: 280931

NCBI Accession: NM_001014385, NP_001014407

UniProt: Q03255