EGFL7 Protein (His tag)
Quick Overview for EGFL7 Protein (His tag) (ABIN1589763)
Target
See all EGFL7 ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This EGFL7 protein is labelled with His tag.
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Purpose
- Recombinant Human VE-Statin/EGFL7 Protein
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Sequence
- HHHHHHTEHA YRRSPGLAPA RPRYACCPGW KRTSGLPGAC GAAICQPPCR NGGSCVQPGR CRCPAGWRGD TCQSDVDECS ARRGGCPQRC VNTAGSYWCQ CWEGHSLSAD GTLCVPKGGP PRVAPNPTGV DSAMKEEVQR LQSRVDLLEE KLQLVLAPLH SLASQALEHG LPDPGSLLVH SFQQLGRIDS LSEQISFLEE QLGSCSCKKD S
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Specificity
- Chromosomal location:9q34.3
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Characteristics
- Length (aa):211
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EGF-Like-Domain, Multiple 7 (EGFL7) (AA 24-273) protein (GST tag)
EGFL7 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
EGF-Like-Domain, Multiple 7 (EGFL7) (AA 24-273) (Active) protein (His tag)EGFL7 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE Active
EGF-Like-Domain, Multiple 7 (EGFL7) (AA 24-273) protein (His-IF2DI Tag)EGFL7 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
EGF-Like-Domain, Multiple 7 (EGFL7) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)EGFL7 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Cytokines & Growth Factors
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- water,The lyophilized human EGFL7 should be reconstituted in water to a concentration of not lower than 50 μg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C,-80 °C
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Storage Comment
- Lyophilized samples are stable for greater than six months at -20°C to -70°C. Reconstituted EGFL7 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles!
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Expiry Date
- 6 months
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- EGFL7 (EGF-Like-Domain, Multiple 7 (EGFL7))
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Alternative Name
- VE-Statin/EGFL7
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Background
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Synonyms: EGFL7, NEU1, ZNEU1, VE-STATIN, RP11-251M1.2, NOTCH4-like protein
Description: EGFL7 (VE-Statin) is an ~ 30 kDa secreted protein that contains an Emilin-like (EMI) domain (a multimerization motif), and two epidermal growth factor (EGF) domains, one of which binds calcium. Based on these domains, it has been hypothesized that EGFL7 may self-assemble like extracellular matrix (ECM) proteins and, thus, could incorporate into ECM. EGFL7 has been reported to stimulate cell adhesion as well as motility in a manner similar to ECM proteins. EGFL7 has been shown to be primarily expressed by developing ECs but also by primordial germ cells and some central nervous system neurons. Interestingly, EGFL7 expression markedly decreases in ECs in postnatal life, but can be strongly up-regulated after various tissue injuries that lead to increased angiogenic responses.
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Molecular Weight
- 22.75 kDa
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Gene ID
- 51162
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NCBI Accession
- NM_016215, NP_057299
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UniProt
- Q9UHF1
Target
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