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IL10RB Protein (C-Term, Extracellular Domain)

IL10RB Origin: Mouse Host: HEK-293 Cells Recombinant > 90 %, as determined by SDS-PAGE and HPLC
Catalog No. ABIN1684696
  • Target See all IL10RB Proteins
    IL10RB (Interleukin 10 Receptor, beta (IL10RB))
    Protein Type
    Recombinant
    Protein Characteristics
    C-Term, Extracellular Domain
    Origin
    • 10
    • 3
    • 3
    Mouse
    Source
    • 5
    • 5
    • 3
    • 2
    • 1
    HEK-293 Cells
    Sequence
    MAPCVAGWLG GFLLVPALGM IPPPEKVRMN SVNFKNILQW EVPAFPKTNL TFTAQYESYR SFQDHCKRTA STQCDFSHLS KYGDYTVRVR AELADEHSEW VNVTFCPVED TIIGPPEMQI 130140150160170180ESLAESLHLR FSAPQIENEP ETWTLKNIYD SWAYRVQYWK NGTNEKFQVV SPYDSEVLRN 1900010203040LEPWTTYCIQ VQGFLLDQNR TGEWSEPICE RTGNDEITPS WIVAIILIVS VLVVFLFLLG 5060708090300CFVVLWLIYK KTKHTFRSGT SLPQHLKEFL GHPHHSTFLL FSFPPPEEAE VFDKLSIISE 310320330340ESEGSKQSPE DNCASEPPSD PGPRELESKD EAPSPPHDDP KLLTSTSEV
    Specificity
    DNA sequence encoding extracellular domain of Mouse IL-10RB fused to a C-terminal polyHis tag was expressed in HEK cells.
    Characteristics
    Recombinant Mouse Interleukin-10RB is a monomer consisting of12 amino acid residue subunits, and migrates as an approximately 46 kDa protein under reducing conditions in SDS-PAGE.
    Purity
    > 90 %, as determined by SDS-PAGE and HPLC
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than 0.1 ng/µg(1EU/µg).
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  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
    Buffer
    PBS solution pH 7.4.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    The lyophilized protein is stable for at least years from date of receipt at -20 °C. Upon reconstitution, this cytokine can be stored in working aliquots at - 8 °C for one month, or at -20 °C for six months, with a carrier protein without detectable loss of activity.
    Expiry Date
    12-24 months
  • Target
    IL10RB (Interleukin 10 Receptor, beta (IL10RB))
    Alternative Name
    IL10RB (IL10RB Products)
    Synonyms
    IL10R2 Protein, IL10RB Protein, il10r2 Protein, CDW210B Protein, CRF2-4 Protein, CRFB4 Protein, D21S58 Protein, D21S66 Protein, IL-10R2 Protein, 6620401D04Rik Protein, AI528744 Protein, Crfb4 Protein, D16H21S58 Protein, D21S58h Protein, Il10r2 Protein, RGD1560373 Protein, interleukin 10 receptor subunit beta Protein, interleukin 10 receptor subunit beta S homeolog Protein, interleukin-10 receptor subunit beta Protein, interleukin 10 receptor, beta Protein, IL10RB Protein, il10rb.S Protein, LOC473966 Protein, LOC478404 Protein, il10rb Protein, Il10rb Protein
    Background
    TNF-beta TNF-beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands and signals through TNFR1 and TNFR2. TNF-beta is produced by activated T and B lymphocytes, and has similar activities to TNF-alpha. Like TNF-alpha TNF-beta is involved in the regulation of various biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-beta is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-beta which effectively anchors the TNF-beta to the cell surface. TNF-beta is cytotoxic to a wide range of tumor cells.
    UniProt
    Q61190
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