Vitamin D-Binding Protein Protein (GC) (AA 17-474) (His tag)

Catalog No. ABIN1691338

Recombinant Vitamin D-Binding Protein protein expressed in Human Cells.

Quick Overview for Vitamin D-Binding Protein Protein (GC) (AA 17-474) (His tag) (ABIN1691338)

Target: Vitamin D-Binding Protein (GC)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 17-474

Purification tag / Conjugate: This Vitamin D-Binding Protein protein is labelled with His tag.

Purpose: Recombinant Human Vitamin D-Binding Protein/VDB/Gc-globulin (C-6His)

Sequence: LERGRDYEKN KVCKEFSHLG KEDFTSLSLV LYSRKFPSGT FEQVSQLVKE VVSLTEACCA EGADPDCYDT RTSALSAKSC ESNSPFPVHP GTAECCTKEG LERKLCMAAL KHQPQEFPTY VEPTNDEICE AFRKDPKEYA NQFMWEYSTN YGQAPLSLLV SYTKSYLSMV GSCCTSASPT VCFLKERLQL KHLSLLTTLS NRVCSQYAAY GEKKSRLSNL IKLAQKVPTA DLEDVLPLAE DITNILSKCC ESASEDCMAK ELPEHTVKLC DNLSTKNSKF EDCCQEKTAM DVFVCTYFMP AAQLPELPDV ELPTNKDVCD PGNTKVMDKY TFELSRRTHL PEVFLSKVLE PTLKSLGECC DVEDSTTCFN AKGPLLKKEL SSFIDKGQEL CADYSENTFT EYKKKLAERL KAKLPDATPT ELAKLVNKRS DFASNCCSIN SPPLYCDSEI DAELKNILVD HHHHHH

Characteristics: Recombinant Human Vitamin D-Binding Protein is produced by our Mammalian expression system and the target gene encoding Leu17-Leu474 is expressed with a 6His tag at the C-terminus.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4.

Storage: 4 °C,-20 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 weeks

Target Details

Target: Vitamin D-Binding Protein (GC)

Alternative Name: Vitamin D-Binding Protein

Sub Type: Fusionprotein

Background: Alternative Names: Vitamin D-Binding Protein, DBP, VDB, Gc-Globulin, Group-Specific Component, GCVitamin D-Binding Protein (DBP) is a member of the ALB/AFP/VDB family. DBP is a secreted protein and contains three albumin domains. The primary structure contains 28 cysteine residues forming multiple disulfide bonds. DBP acts as a multifunctional protein found in plasma, ascitic fluid, cerebrospinal fluid, and urine and on the surface of many cell types. DBP binds to vitamin D and its plasma metabolites and transports them to target tissues. DBP associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes.
Alternative Names: Vitamin D-Binding Protein, DBP, VDB, Gc-Globulin, Group-Specific Component, GC

Molecular Weight: 52.3 kDa

UniProt: P02774

Pathways: Metabolism of Steroid Hormones and Vitamin D, Monocarboxylic Acid Catabolic Process