KIT Ligand Protein (KITLG) (AA 26-214) (His tag)

Catalog No. ABIN1691690

This Recombinant KIT Ligand protein is produced in Human Cells.

Quick Overview for KIT Ligand Protein (KITLG) (AA 26-214) (His tag) (ABIN1691690)

Target: KIT Ligand (KITLG)

Protein Type: Recombinant

Origin: Human

Source: Human Cells

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 26-214

Purification tag / Conjugate: This KIT Ligand protein is labelled with His tag.

Purpose: Recombinant Human Stem Cell Factor/SCF/c-Kit Ligand (C-6His)

Sequence: EGICRNRVTN NVKDVTKLVA NLPKDYMITL KYVPGMDVLP SHCWISEMVV QLSDSLTDLL DKFSNISEGL SNYSIIDKLV NIVDDLVECV KENSSKDLKK SFKSPEPRLF TPEEFFRIFN RSIDAFKDFV VASETSDCVV SSTLSPEKDS RVSVTKPFML PPVAASSLRN DSSSSNRKAK NPPGDSSLHV DHHHHHH

Characteristics:

Recombinant Human Stem Cell Factor/SCF/c-Kit Ligand (C-6His)

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: KIT Ligand (KITLG)

Alternative Name: Stem Cell Factor/SCF

Background: Recombinant Human Stem Cell Factor/SCF is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu26-His214) of Human KITLG fused with a polyhistidine tag at the C-terminus.
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultures and has been shown to act synergistically with colony stimulating factors.

Molecular Weight: 22 kDa

UniProt: P21583

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway