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CTCF Protein (AA 1-154)

CTCF Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691993
  • Target See all CTCF Proteins
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-154
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purpose
    Recombinant Human Transcriptional Repressor CTCF/CTCF
    Sequence
    MEGDAVEAIV EESETFIKGK ERKTYQRRRE GGQEEDACHL PQNQTDGGEV VQDVNSSVQM VMMEQLDPTL LQMKTEVMEG TVAPEAEAAV DDTQIITLQV VNMEEQPINI GELQLVQVPV PVTVPVATTS VEELQGAYEN EVSKEGLAES EPMI
    Characteristics

    Recombinant Human Transcriptional Repressor CTCF/CTCF

    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
    Top Product
    Discover our top product CTCF Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    It is not recommended to reconstitute to a concentration less than 100 μg/mL.
    Dissolve the lyophilized protein in ddH2O.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
    Buffer
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
    Handling Advice
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    Storage
    4 °C/-20 °C/-80 °C
    Storage Comment
    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
    Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Target
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    Alternative Name
    Transcriptional Repressor CTCF/CTCF (CTCF Products)
    Synonyms
    im:7152666 Protein, CTCF Protein, xctcf Protein, AW108038 Protein, CCCTC-binding factor Protein, CCCTC-binding factor (zinc finger protein) Protein, CTCF Protein, ctcf Protein, Ctcf Protein
    Background
    Recombinant Human Transcriptional Repressor CTCF/CTCF is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ile154) of Human CTCF.
    Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in primary spermatocytes. CTCF is involved in transcriptional regulation by binding to chromatin insulators and preventing interaction between promoter and nearby enhancers and silencers. CTCF plays an essential role in oocyte and preimplantation embryo development by activating or repressing transcription. In addition, CTCF is also indispensable in the epigenetic regulation and chromatin remodeling.
    Molecular Weight
    16.9 kDa
    UniProt
    P49711
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