FGF17 Protein (AA 23-216)

Catalog No. ABIN1692377

Product Details

Target: FGF17 (Fibroblast Growth Factor 17 (FGF17))

Protein Type: Recombinant

Protein Characteristics: AA 23-216

Origin: Human

Source: Escherichia coli (E. coli)

Purpose: Recombinant Human Fibroblast Growth Factor 17/FGF-17

Sequence: MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT

Characteristics: Recombinant Human Fibroblast Growth Factor 17/FGF-17 is produced with our E. coli expression system. The target protein is expressed with sequence (Thr23-Thr216) of Human FGF17.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 5 months

Target Details

Target: FGF17 (Fibroblast Growth Factor 17 (FGF17))

Alternative Name: FGF17 (FGF17 Products)

Synonyms: FGF17 Protein, FGF-13 Protein, HH20 Protein, fgf17b Protein, zgc:101759 Protein, fibroblast growth factor 17 Protein, FGF17 Protein, Fgf17 Protein, fgf17 Protein

Background: Fibroblast Growth Factor 17 (FGF17) is a member of the heparin-binding growth factors family that is prominently expressed in the cerebellum and cortex. Proteins of this family possess broad mitogenic and cell survival activities and they are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF17 plays an important role in the regulation of embryonic development and it acts as signaling molecule in the induction and patterning of the embryonic brain. In addition, FGF17 stimulates the proliferation and activation of cells that express FGF receptors.
Alternative Names: Fibroblast Growth Factor 17, FGF-17, FGF17

Molecular Weight: 22.6 kDa

UniProt: O60258

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway