Cytokeratin 19 Protein
Quick Overview for Cytokeratin 19 Protein (ABIN1880333)
Target
See all Cytokeratin 19 (KRT19) ProteinsProtein Type
Biological Activity
Origin
Source
Application
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Purification
- Purified
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Keratin 19 (KRT19) (AA 1-403) protein (His tag)
custom-made KRT19 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Keratin 19 (KRT19) (AA 1-400) protein (His tag)custom-made KRT19 Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Keratin 19 (KRT19) (AA 310-399) (Active) protein (His tag)KRT19 Origin: Dog Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC Active
Keratin 19 (KRT19) (AA 1-400) protein (GST tag)KRT19 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Tris-HCl ( pH 7.4±0.2)with 0.2 % Sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Shipat 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))
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Alternative Name
- Cytokeratin 19
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Background
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Synonyms: Keratin type I cytoskeletal 19, Cytokeratin-19, CK-19, Keratin-19, K19, KRT19, CK19
Description: Purified human CK19 protein.
Background: Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. It has been shown to be an independent prognostic factor for pancreatic neuroendocrine tumors, especially the insulin-negative tumors. CK19 positive tumors are associated with poor outcome irrespective of the established pathologic parameters such as size, mitoses, lymphovascular invasion, and necrosis.The low-molecular-weight cytokeratin (CK) protein CK19 has been shown to have diagnostic use and prognostic significance in some types of human malignancy.Cytokeratin-19 alone and its combinations with other markers were more sensitive in accurate diagnosis of papillary carcinoma than the other combinations.
Target
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