C-Peptide Protein

Catalog No. ABIN1880359

Recombinant C-Peptide protein expressed in Escherichia coli (E. coli).

Quick Overview for C-Peptide Protein (ABIN1880359)

Target: C-Peptide

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: ELISA

Purity: >95 % by HPLC & SDS-PAGE

Product Details

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM PBS( pH 7.5) without preservative.

Preservative: Without preservative

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: C-Peptide

Background:

Synonyms: C-peptide, Connecting peptide

Description: Recombinant full length human C-Peptide protein.

Background: Connecting peptide, or C-peptide, is a short 31-amino-acid protein that connects insulin's A-chain to its B-chain in the proinsulin molecule. C-peptide has been shown to bind to the surface of a number of cell types such as neuronal, endothelial, fibroblast and renal tubular, at nanomolar concentrations to a receptor that is likely G-protein-coupled. It has been found to exert beneficial effects in many tissues affected by diabetic microvascular complications, including the kidneys. C-peptide at physiological concentrations effectively reduces diabetes-induced glomerular hyperfiltration via constriction of the afferent arteriole, dilation of the efferent arteriole, and inhibition of tubular reabsorption in experimental models of type 1 diabetes.