Epididymis Protein 4 (HE-4) (Active) Protein
Quick Overview for Epididymis Protein 4 (HE-4) (Active) Protein (ABIN1880368)
Target
Protein Type
Biological Activity
Origin
Source
Application
Purity
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Tris-HCL ( pH 7.4±0.2) with 0.2 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C,-80 °C
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Storage Comment
- Shipat 4°C. Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
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- Epididymis Protein 4 (HE-4)
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Alternative Name
- Epididymis Protein 4
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Background
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Synonyms: Human epididymis protein 4, HE4, WAP four-disulfide core domain protein 2, WFDC2
Description: Recombinant full length human HE4 protein with molecular weight 14 kDa.
Background: WAP four-disulfide core domain protein 2,also known as Human Epididymis Protein 4 (HE4) is a protein that in humans is encoded by the WFDC2 gene. This gene is amplified in ovarian carcinomas, whereas its expression in normal tissues, including ovary, is low. Although the function of the HE4 protein is unknown,it is a member of a family of stable 4-disulfide core proteins that are secreted at high levels.HE4 is a secreted glycoprotein that is overexpressed by serous and endometrioid EOCs(epithelial ovarian carcinomas). Its expression in cortical inclusion cysts suggests that formation of Mullerian epithelium is a prerequisite step in the development of some types ofEOCs.
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Molecular Weight
- 14 kDa
Target
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