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NGFB Protein

This Native NGFB protein is expressed in Mouse.
Catalog No. ABIN1880418

Quick Overview for NGFB Protein (ABIN1880418)

Target

See all NGFB Proteins
NGFB (Nerve Growth Factor beta (NGFB))

Protein Type

Native

Biological Activity

Active

Origin

  • 15
  • 9
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Mouse

Source

  • 16
  • 8
  • 3
  • 2
  • 1
  • 1
  • 1
Mouse

Purity

> 95 % by SDS-PAGE
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitute with sterile 18 mΩ/cm^3 H2O.

    Buffer

    10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)

    Preservative

    Without preservative

    Storage

    4 °C
  • Target

    NGFB (Nerve Growth Factor beta (NGFB))

    Alternative Name

    NGF beta

    Background

    Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF consists of 3 types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight complex. It is mainly expressed in Sertoli and interstitial cells. The proforms of NGF are secreted and cleaved extracellularly by the serine protease plasmin and by selective matrix metalloproteinases. NGF is important for the growth, maintenance, and survival of certain target neurons (nerve cells). It also functions as a signaling molecule.

    Molecular Weight

    26.5 kDa

    Pathways

    NF-kappaB Signaling, RTK Signaling, Regulation of Cell Size
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