Osteopontin Protein

Catalog No. ABIN1880427

This Recombinant Osteopontin protein is expressed in Escherichia coli (E. coli).

Quick Overview for Osteopontin Protein (ABIN1880427)

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS), ELISA

Purity: >95 % by SDS-PAGE

Product Details

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM Tris-HCl ( pH 7.4±0.2) with 0.2 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Shipat 4°C.Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.

Target Details

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Alternative Name: Osteopontin

Background:

Synonyms: Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, SPP1, Urinary stone protein, Uropontin, BNSP, OPN, BSPI, ETA-1

Description: Recombinant full length human OPN protein with molecular weight 35 kDa.

Background: Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), secreted phosphoprotein 1 (SPP1), is a human gene product. The gene has 7 exons, spans 5 kilobases in length and in humans it is located on 4q13. The protein is composed of ~300 amino acids residues and has ~30 carbohydrate residues attached including 10 sialic acid residues, which are attached to the protein during post-translational modification in the Golgi apparatus. Osteopontin has been implicated as an important factor in bone remodeling. Specifically, research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones.

Molecular Weight: 35 kDa

Pathways: Regulation of Cell Size