SENP2 Protein (AA 363-589)

Catalog No. ABIN1880578

Recombinant SENP2 protein expressed in Escherichia coli (E. coli).

Quick Overview for SENP2 Protein (AA 363-589) (ABIN1880578)

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purity: > 95 % as determined by reducing SDS-PAGE.

Product Details

Protein Characteristics: AA 363-589

Purpose: Recombinant Human Sentrin-Specific Protease 2/SENP2

Sequence: DDLLELTEDM EKEISNALGH GPQDEILSSA FKLRITRGDI QTLKNYHWLN DEVINFYMNL LVERNKKQGY PALHVFSTFF YPKLKSGGYQ AVKRWTKGVN LFEQEIILVP IHRKVHWSLV VIDLRKKCLK YLDSMGQKGH RICEILLQYL QDESKTKRNS DLNLLEWTHH SMKPHEIPQQ LNGSDCGMFT CKYADYISRD KPITFTQHQM PLFRKKMVWE ILHQQLL

Characteristics: Recombinant Human Sentrin-specific protease 2 is produced by our E.coli expression system and the target gene encoding Asp363-Leu589 is expressed.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 um filtered solution of 50 mM HEPES, 5 % Glycerol, pH 7.4.

Handling Advice: minimize freeze-thaw cycles

Storage: -20 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Alternative Name: SENP2

Sub Type: Fusionprotein

Background: Alternative Names: Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2.SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway.
Alternative Names: Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Sentrin/SUMO-specific protease SENP2, KIAA1331, SENP2.

Molecular Weight: 26.8 kDa

UniProt: Q9HC62

Pathways: Chromatin Binding