SNCA Protein (AA 1-140) (HiLyte Fluor 488)
Quick Overview for SNCA Protein (AA 1-140) (HiLyte Fluor 488) (ABIN1882766)
Target
See all SNCA ProteinsProtein Type
Origin
Source
-
-
Protein Characteristics
- AA 1-140
-
Purification tag / Conjugate
- This SNCA protein is labelled with HiLyte Fluor 488.
-
Characteristics
-
The recombinant human alpha-synuclein (1-140) was expressed and purified from E. coli and conjugated with the fluorescence dye HiLyte FluorTM 488.
Green fluorescence.
Excitation/Emission wavelengths= 503 nm/525 nm -
Purification
- Purified from E. Coli.
-
-
Want other Options for this Protein ?
!Discover Our Predefined Custom Proteins and Custom Protein Services!ProductExpression SystemConjugateOriginPrice starts atExpression System HEK-293 CellsConjugate His tagOrigin HumanPrice starts at $13,686.36Expression System Cell-free protein synthesis (CFPS)Conjugate Strep TagOrigin HumanPrice starts at $20,480.57Your project requires further customization? Contact us and discover our custom protein solutions
-
-
-
Restrictions
- For Research Use only
-
-
-
Handling Advice
- Protect from light!
-
Storage
- -80 °C
-
-
- SNCA (Synuclein, alpha (SNCA))
-
Alternative Name
- alpha-Synuclein
-
Background
- Parkinson's disease (PD) is predominantly a movement disorder resulting from degeneration of dopaminergic neurons in the substantia nigra. The cause of the disease is unknown, but substantial evidence suggests that the aggregation of alpha-synuclein is a critical step in the etiology of PD. alpha-Synuclein is an abundant protein of 140 residues that is present in high concentration at presynaptic terminals and is found in both soluble and membrane-associated fractions of the brain. Several possible functions have been suggested, among which are vesicle release and trafficking. In vitro incubation in the presence of salt (i.e. 0.1 M NaCl) with agitation causes alpha-synuclein to form fibrils.
-
NCBI Accession
- NP_000336
-
Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
-