SNCA Protein (full length)
Quick Overview for SNCA Protein (full length) (ABIN1882770)
Target
See all SNCA ProteinsProtein Type
Origin
Source
Application
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Protein Characteristics
- full length
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Characteristics
- The sequence corresponding to the full length human alpha-synuclein protein without affinity tag was expressed in E. Coli.
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Purification
- Purified from bacterial lysate using proprietary method.
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Endotoxin Level
- EndoFree
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Synuclein, alpha (SNCA) (A53T) (Active) protein
SNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (full length) (Active) proteinSNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant >95% pure using SDS-PAGE analysis. SDS, WB, in vitro, in vivo Active
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)custom-made SNCA Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)custom-made SNCA Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Synuclein, alpha (SNCA) proteinSNCA Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Synuclein, alpha (SNCA) (AA 1-140) protein (His tag)SNCA Origin: Rat Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Synuclein, alpha (SNCA) (active) proteinSNCA Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % pure SDS
Synuclein, alpha (SNCA) (AA 31-140) protein (GST tag)SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Synuclein, alpha (SNCA) (AA 1-140) protein (GST tag)SNCA Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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Restrictions
- For Research Use only
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Storage
- -80 °C
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- SNCA (Synuclein, alpha (SNCA))
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Alternative Name
- alpha-Synuclein
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Background
- Alpha-synuclein is a major component of Lewy bodies in the affected neurons in Parkinson's disease. This protein has a mass of 14.5 kDa (140 amino acids long) and consists of a conserved degenerative amino-terminal domain and an acidic carboxyl-terminal with higher sequence divergence. alpha-synuclein is predominantly expressed in the brain: specifically in cerebellum, thalamus, neocortex, hippocampus, and striatum regions. Other tissues express alpha-synuclein at very low levels. The physiological role of alpha-ynuclein is not yet well understood. However, the presence of imperfect KTKEGV lipid interacting repeats suggests that it may be involved in synaptic vesicle homeostasis
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Molecular Weight
- 14.5 kDa
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NCBI Accession
- NP_000336
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Pathways
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
Target
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