MMP12 Protein (AA 106-267, Catalytic Domain)
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- Target See all MMP12 Proteins
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 106-267, Catalytic Domain
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Characteristics
- The sequence corresponding to the catalytic domain (aa 106-267) of Human MMP-12 was expressed in E. Coli.
- Purification
- Purified from bacterial lysate and refolded using proprietary technique.
- Top Product
- Discover our top product MMP12 Protein
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Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 1-470) protein (GST tag)
MMP12 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 292-401) protein (GST tag)MMP12 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) protein (His tag)MMP12 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 106-470) protein (His tag)Crystallography grade MMP12 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12) (AA 110-473) protein (His tag)Crystallography grade MMP12 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Storage
- -80 °C
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- Target
- MMP12 (Matrix Metallopeptidase 12 (Macrophage Elastase) (MMP12))
- Alternative Name
- MMP-12 (MMP12 Products)
- Synonyms
- MMP12 Protein, AV378681 Protein, Mmel Protein, Mme Protein, HME Protein, ME Protein, MME Protein, MMP-12 Protein, matrix metallopeptidase 12 Protein, MMP12 Protein, Mmp12 Protein
- Background
- Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated zinc endopeptidases capable of digesting extracellular matrix components. MMP-12 (macrophage elastase) is involved in smoke-induced emphysema, tumor and other diseases. MMP-12 is secreted as a 54 kDa zymogen and becomes the mature 54 kDa active form after proteolytic cleavage. MMP-12 has a broad range of substrates, including alpha-1 proteinase inhibitor, alpha-2 antiplasmin, plasminogen activator inhibitor-2, collagen IV, laminin, fibronectin, elastin, but not interstitial collagens.
- Molecular Weight
- 18 kDa
- NCBI Accession
- NP_002417
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