Betacellulin Protein (BTC) (AA 32-111)

Catalog No. ABIN2017686

This Recombinant Betacellulin protein is expressed in HEK-293T Cells.

Quick Overview for Betacellulin Protein (BTC) (AA 32-111) (ABIN2017686)

Target: Betacellulin (BTC)

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: HEK-293T Cells

Purity: > 95 % as analyzed by SDS-PAGE.

Product Details

Protein Characteristics: AA 32-111

Characteristics: ED50 < 4 pg/mL, measured in a cell proliferation assay using 3T3 cells.

Endotoxin Level: < 0.2 EU/μg, determined by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Storage: -80 °C

Storage Comment: Lyophilized recombinant Human Betacellulin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Betacellulin should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Expiry Date: 6 months

Target Details

Target: Betacellulin (BTC)

Alternative Name: Betacellulin

Background: Betacellulin (BTC) is a member of the EGF family of cytokines that also includes EGF, TGF-alpha, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin, Heregulin and Neuregulins. At the amino acid sequence level, human mature BTC protein exhibits 80 % identity with mouse BTC protein. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum.
Synonyms: BTC

Molecular Weight: 15-18 kDa, observed by reducing SDS-PAGE.

UniProt: P35070

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway