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Betacellulin Protein (BTC) (AA 32-111)

BTC Origin: Human Host: HEK-293T Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Catalog No. ABIN2017687
  • Target See all Betacellulin (BTC) Proteins
    Betacellulin (BTC)
    Protein Type
    Recombinant
    Biological Activity
    Active
    Protein Characteristics
    AA 32-111
    Origin
    • 14
    • 7
    • 4
    • 2
    • 2
    Human
    Source
    • 13
    • 5
    • 4
    • 3
    • 2
    • 1
    HEK-293T Cells
    Characteristics
    ED50 < 4 pg/mL, measured in a cell proliferation assay using 3T3 cells.
    Purity
    > 95 % as analyzed by SDS-PAGE.
    Endotoxin Level
    < 0.2 EU/μg, determined by LAL method.
    Top Product
    Discover our top product BTC Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Reconstituted in ddH2O or PBS at 100 μg/mL.
    Buffer
    Lyophilized after extensive dialysis against PBS.
    Storage
    -80 °C
    Storage Comment
    Lyophilized recombinant Human Betacellulin remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Betacellulin should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
    Expiry Date
    6 months
  • Target
    Betacellulin (BTC)
    Alternative Name
    Betacellulin (BTC Products)
    Synonyms
    BTC Protein, LOC100228121 Protein, probetacellulin Protein, Bcn Protein, betacellulin Protein, betacellulin, epidermal growth factor family member Protein, BTC Protein, LOC100228121 Protein, Btc Protein
    Background
    Betacellulin (BTC) is a member of the EGF family of cytokines that also includes EGF, TGF-alpha, Amphiregulin, HB-EGF, Epiregulin, Tomoregulin, Heregulin and Neuregulins. At the amino acid sequence level, human mature BTC protein exhibits 80 % identity with mouse BTC protein. BTC is expressed in most tissues including kidney, uterus, liver and pancreas. It is also present in body fluids, including serum, milk, and colostrum.
    Synonyms: BTC
    Molecular Weight
    15-18 kDa, observed by reducing SDS-PAGE.
    UniProt
    P35070
    Pathways
    RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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