IGFBP2 Protein (AA 40-325) (His tag)
Quick Overview for IGFBP2 Protein (AA 40-325) (His tag) (ABIN2017974)
Target
See all IGFBP2 ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 40-325
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Purification tag / Conjugate
- This IGFBP2 protein is labelled with His tag.
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Characteristics
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ED50 < 2 μg/mL, measured in a bioassay using FDC-P1 cells in the presence of 15 ng/mL human IGF-II.
AA 40-325, expressed with C-terminal 6xHis. -
Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) (AA 35-305) protein (His tag)
IGFBP2 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) (AA 36-325) protein (His tag)IGFBP2 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) (AA 33-325) protein (His tag)IGFBP2 Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) (AA 1-328) protein (GST tag)IGFBP2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2) protein (Fc Tag)IGFBP2 Origin: Mouse Host: HEK-293 Cells Recombinant > (65.9+24.5) % as determined by SDS-PAGE
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant human IGF-BP-2, Hisremains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human IGF-BP-2, His should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))
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Background
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IGF-BP-2,also known as Insulin-like growth factor-binding protein 2, IBP-2 and BP-2, is a cysteine-rich secreted protein belonging to the IGF-binding protein superfamily. It is expressed by the central nervous system, bone cells and reproductive tissues. IGF-BP-2 binds to both IGF-I and IGF-II, with a much higher binding affinity to IGF-II than IGF-I. IGF-BP-2 has been shown to inhibitand stimulate the growth promoting effects of IGFs, thus serving as a regulator for IGF distribution, function and activity.
Synonyms: Insulin-like growth factor-binding protein 2, IBP-2, BP-2 -
Molecular Weight
- 6-20 kDa, observed by reducing SDS-PAGE.
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UniProt
- P18065
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Pathways
- Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation
Target
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