IL1A Protein (AA 116-270)
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- Target See all IL1A Proteins
- IL1A (Interleukin 1 alpha (IL1A))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 116-270
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Origin
- Rat
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Source
- CHO Cells
- Characteristics
- ED50 <5 pg/mL, measured in a proliferation assay using D10S cells.
- Purity
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL1A Protein
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Interleukin 1 alpha (IL1A) (Active) protein
IL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Interleukin 1 alpha (IL1A) (AA 113-271) proteinIL1A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 113-271) protein (His tag)IL1A Origin: Cynomolgus Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Interleukin 1 alpha (IL1A) (AA 115-270) protein (His tag)IL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Interleukin 1 alpha (IL1A) (AA 1-271) protein (GST tag)IL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) (AA 172-271) protein (GST tag)IL1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Interleukin 1 alpha (IL1A) proteinIL1A Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
Interleukin 1 alpha (IL1A) proteinIL1A Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Storage
- -80 °C
- Storage Comment
- Lyophilized recombinant Rat Interleukin-1 alpha remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Rat Interleukin-1 alpha should be stable up to 1 week at 4°C or up to 2 months at -20°C.
- Expiry Date
- 6 months
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- Target
- IL1A (Interleukin 1 alpha (IL1A))
- Alternative Name
- Interleukin-1alpha (IL-1alpha) (IL1A Products)
- Synonyms
- IL-1A Protein, IL1 Protein, IL1-ALPHA Protein, IL1F1 Protein, IL-6 Protein, Il-1a Protein, IL-1 alpha Protein, IL-1alpha Protein, L1A Protein, interleukin 1 alpha Protein, interleukin 6 Protein, IL1A Protein, IL6 Protein, Il1a Protein
- Background
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Interleukin-1 alpha (IL-1α), is produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta bind to the same receptor and have similar if not identical biological properties. These cytokines have a broad range of activities including stimulation of thymocyte proliferation via IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity, and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine.
Synonyms: Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF) - Molecular Weight
- 17-22 kDa, observed by reducing SDS-PAGE.
- UniProt
- P16598
- Pathways
- NF-kappaB Signaling, Autophagy, Cancer Immune Checkpoints
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