FGF7 Protein (AA 32-194)

Catalog No. ABIN2018177

This Recombinant FGF7 protein is produced in CHO Cells.

Quick Overview for FGF7 Protein (AA 32-194) (ABIN2018177)

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Protein Type: Recombinant

Biological Activity: Active

Origin: Human

Source: CHO Cells

Purity: > 95 % as analyzed by SDS-PAGE and HPLC.

Product Details

Protein Characteristics: AA 32-194

Characteristics: ED50 < 1 ng /mL, measured in a proliferation assay using 4MBr5 cells.

Endotoxin Level: < 0.2 EU/μg, determined by LAL method.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Storage: -80 °C

Storage Comment: Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Expiry Date: 6 months

Target Details

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Alternative Name: Keratinocyte Growth Factor (KGF)

Background: Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion.
Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7

Molecular Weight: 16-18 kDa, observed by reducing SDS-PAGE.

UniProt: P21781

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway