CCL20 Protein
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- Target See all CCL20 Proteins
- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Sequence
- ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM
- Characteristics
- Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/mL.
- Purity
- > 96 % by SDS-PAGE and HPLC analyses.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- < 1 EU/μg of rMuMIP-3μ/CCL20 as determined by LAL method.
- Top Product
- Discover our top product CCL20 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
- Buffer
- Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
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- Target
- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
- Alternative Name
- MIP-3alpha/CCL20 (CCL20 Products)
- Synonyms
- MIP-3ALPHA Protein, CCL20 Protein, si:dkey-150o13.1 Protein, CKb4 Protein, LARC Protein, MIP-3-alpha Protein, MIP-3a Protein, MIP3A Protein, SCYA20 Protein, ST38 Protein, MIP-3A Protein, MIP-3[a] Protein, Scya20 Protein, exodus-1 Protein, C-C motif chemokine ligand 20 Protein, chemokine (C-C motif) ligand 20b Protein, chemokine (C-C motif) ligand 20 Protein, CCL20 Protein, ccl20b Protein, Ccl20 Protein
- Background
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MIP-3 alpha/CCL20, also known as LARC (Liver and Activation-regulated Chemokine) and as Exodus, is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.
Synonyms: Macrophage Inflammatory Protein-3 alpha, CCL20, LARC, Exodus-1 - Molecular Weight
- 8.0 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids.
- Pathways
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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