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CCL20 Protein

CCL20 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 96 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN2018256
  • Target See all CCL20 Proteins
    CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 17
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Mouse
    Source
    • 28
    • 2
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM
    Characteristics
    Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/mL.
    Purity
    > 96 % by SDS-PAGE and HPLC analyses.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    < 1 EU/μg of rMuMIP-3μ/CCL20 as determined by LAL method.
    Top Product
    Discover our top product CCL20 Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
    Buffer
    Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    4 °C/-20 °C
    Storage Comment
    This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C.
  • Target
    CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
    Alternative Name
    MIP-3alpha/CCL20 (CCL20 Products)
    Synonyms
    MIP-3ALPHA Protein, CCL20 Protein, si:dkey-150o13.1 Protein, CKb4 Protein, LARC Protein, MIP-3-alpha Protein, MIP-3a Protein, MIP3A Protein, SCYA20 Protein, ST38 Protein, MIP-3A Protein, MIP-3[a] Protein, Scya20 Protein, exodus-1 Protein, C-C motif chemokine ligand 20 Protein, chemokine (C-C motif) ligand 20b Protein, chemokine (C-C motif) ligand 20 Protein, CCL20 Protein, ccl20b Protein, Ccl20 Protein
    Background
    MIP-3 alpha/CCL20, also known as LARC (Liver and Activation-regulated Chemokine) and as Exodus, is a CC chemokine that is expressed in the liver, lymph nodes, appendix, PBL and lung and can signal through the CCR6 receptor. MIP-3 alpha is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors.
    Synonyms: Macrophage Inflammatory Protein-3 alpha, CCL20, LARC, Exodus-1
    Molecular Weight
    8.0 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids.
    Pathways
    The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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