PDGFD Protein (AA 250-370)
Quick Overview for PDGFD Protein (AA 250-370) (ABIN2018313)
Target
See all PDGFD ProteinsProtein Type
Biological Activity
Origin
Source
Purity
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Protein Characteristics
- AA 250-370
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Characteristics
- ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
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Endotoxin Level
- < 0.2 EU/μg, determined by LAL method.
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Platelet Derived Growth Factor D (PDGFD) (AA 1-364) protein (GST tag)
PDGFD Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor D (PDGFD) (AA 24-370) protein (His-IF2DI Tag)PDGFD Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Platelet Derived Growth Factor D (PDGFD) (AA 24-123) protein (GST tag)PDGFD Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Platelet Derived Growth Factor D (PDGFD) (AA 250-370) protein (Fc Tag)PDGFD Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Platelet Derived Growth Factor D (PDGFD) (AA 19-370) protein (His tag)PDGFD Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Storage
- -80 °C
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Storage Comment
- Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Expiry Date
- 6 months
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- PDGFD (Platelet Derived Growth Factor D (PDGFD))
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Background
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PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Synonyms: platelet-derived growth factor D, IEGF, SCDGFB -
Molecular Weight
- 19-21 kDa, observed by reducing SDS-PAGE.
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UniProt
- Q9GZP0
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Pathways
- RTK Signaling, Platelet-derived growth Factor Receptor Signaling
Target
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